The association between the dietary pattern in abdominal obesity based on visceral fat index and dyslipidaemia in the Henan Rural Cohort Study

The association between the dietary pattern in abdominal obesity based on visceral fat index and dyslipidaemia in the Henan Rural Cohort Study
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河南农村队列研究基于内脏脂肪指数的腹型肥胖膳食模式与血脂异常的关系

DOI:
10.1017/s0007114521003640
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发表时间:
2021-09
影响因子:
3.6
通讯作者:
Wenjie Li
Wenjie Li
中科院分区:
医学3区
文献类型:
--
作者:
Yuan Xue;Chang Liu;Shanbin Pang;Zhenxing Mao;Dongdong Zhang;Jiaojiao Gao;Jisong Lin;Chongjian Wang;Xing Li;Wenjie Li

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摘要。本研究旨在探讨以内脏脂肪指数(VFI)为因变量的降秩回归(RRR)得出的腹部肥胖饮食模式与中国河南农村成年人血脂异常之间的关系。从河南省农村队列研究中选取年龄在18-79岁之间的29538人。RRR分析用于确定饮食模式;应用Logistic回归分析和限制三次样条回归模型分析腹部肥胖患者饮食模式与血脂异常之间的关系。使用VFI作为中介来评估中介效果。腹部肥胖患者的饮食模式以高碳水化合物和红肉摄入,低新鲜水果、蔬菜、牛奶等消耗为特征。完全调整后,饮食模式得分最高的四分位数与血脂异常风险增加显著相关(OR: 1.33, 95% CI 1.23 - 1.44, Ptrend贫关联Pnon-lin-association = 0.022)。饮食模式评分和VFI之间的剂量反应结果相似。VFI部分介导的间接效应显著(OR: 1.07, 95% CI 1.06 - 1.08)。VIF解释了大约53.3%与饮食模式相关的血脂异常几率。腹部肥胖饮食模式评分正影响VFI和血脂异常;这两种关系都存在剂量反应。腹部肥胖饮食模式评分越高,血脂异常进展越快。此外,VFI在腹型肥胖饮食方式与血脂异常的关系中起部分中介作用。
Abstract. The present study aimed to explore the association between dietary patterns in abdominal obesity obtained by reduced-rank regression (RRR) with visceral fat index (VFI) as a dependent variable and dyslipidemia in rural adults in Henan, China. A total of 29538 people aged 18–79 were selected from the Henan Rural Cohort Study. RRR analysis was used to identify dietary patterns; logistic regression analysis and restricted cubic spline regression models were applied to analyze the association between dietary patterns in abdominal obesity and dyslipidemia. VFI was used as a mediator to estimate the mediation effect. The dietary pattern in abdominal obesity was characterized by high carbohydrate and red meat intake and low consumption of fresh fruits, vegetables, milk, etc. After full adjustment, the highest quartile of dietary pattern scores was significantly associated with an increased risk of dyslipidemia (OR: 1·33, 95 % CI 1·23–1·44, Ptrend Poverall-association Pnon-lin-association = 0·022). The result was similar in dose-response between the dietary pattern scores and VFI. The indirect effect partially mediated by VFI was significant (OR: 1·07, 95 % CI 1·06–1·08). VIF explained approximately 53·3 % of odds of dyslipidemia related to the dietary pattern. Abdominal obesity dietary pattern scores positively affected VFI and dyslipidemia; there was a dose-response in both relationships. Dyslipidemia progression increased with higher abdominal obesity dietary pattern scores. In addition, VFI played a partial mediating role in relationship between abdominal obesity dietary pattern and dyslipidemia.
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