Neuroendocrinology of sexual plasticity in teleost fishes.

Neuroendocrinology of sexual plasticity in teleost fishes.
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DOI:
10.1016/j.yfrne.2010.02.002
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发表时间:
2010-04
影响因子:
7.4
通讯作者:
Godwin, John
Godwin, John
中科院分区:
医学1区
文献类型:
--
作者:
Godwin, John

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性别差异的研究对动物表型的组织和相似遗传模板产生表型变异的调节机制产生了重要的见解。硬骨鱼在脊椎动物中表现出最大的性表达多样性。这种多样性似乎源于性别决定时间的多样性,以及相对于四足脊椎动物,性的组成部分之间较少的功能相互依赖。因此,硬骨鱼模型系统为理解性腺和非性腺对行为和生理变化的影响提供了强有力的模型。本文综述了社会控制的鱼类性别变化和雄性交替表型。这些性模式是信息丰富的自然实验,说明了保守的神经内分泌通路的变化如何引起广泛的生殖适应。迄今为止,已经确定的性别变化和其他男性表型的关键调节因素包括类固醇激素、神经肽GnRH和精氨酸缩宫素,但基因组方法现在也暗示了其他多样性的影响。
The study of sex differences has produced major insights into the organization of animal phenotypes and the regulatory mechanisms generating phenotypic variation from similar genetic templates. Teleost fishes display the greatest diversity of sexual expression among vertebrate animals. This diversity appears to arise from diversity in the timing of sex determination and less functional interdependence among the components of sexuality relative to tetrapod vertebrates. Teleost model systems therefore provide powerful models for understanding gonadal and non-gonadal influences on behavioral and physiological variation. This review addresses socially controlled sex change and alternate male phenotypes in fishes. These sexual patterns are informative natural experiments that illustrate how variation in conserved neuroendocrine pathways can give rise to a wide range of reproductive adaptations. Key regulatory factors underlying sex change and alternative male phenotypes that have been identified to date include steroid hormones and the neuropeptides GnRH and arginine vasotocin, but genomic approaches are now implicating a diversity of other influences as well.
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