Improvisational Movement to Improve Quality of Life in Older Adults With Early-Stage Dementia: A Pilot Study.
Improvisational Movement to Improve Quality of Life in Older Adults With Early-Stage Dementia: A Pilot Study.
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DOI：
10.3389/fspor.2021.796101
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发表时间：
2021
影响因子：
2.7
通讯作者：
Hugenschmidt CE
中科院分区：
文献类型：
--
作者：
Thumuluri D;Lyday R;Babcock P;Ip EH;Kraft RA;Laurienti PJ;Barnstaple R;Soriano CT;Hugenschmidt CE
阿尔茨海默病对生活质量有着深远的影响，不仅影响认知，还影响流动性和社会参与的机会。舞蹈是一种运动形式，可能是唯一适合帮助维持老年人的生活质量，包括那些患有痴呆症，因为它本质上结合了运动，社会参与和认知刺激。在这里，我们描述了IMOVE试验（NCT 03333837，www.clinicaltrials.gov）的试点研究的方法和结果，该临床试验旨在使用即兴舞蹈课程来测试轻度认知障碍（MCI）或早期痴呆症患者的运动和社会参与的影响。该试点研究是一项为期8周的调查，旨在研究即兴舞蹈干预对MCI或早期痴呆症（PWD/MCI）患者及其护理人员（CG）的可行性和潜在影响。该试点旨在评估PWD/MCI及其CG的生活质量，平衡，情绪和功能性大脑网络的变化。参与者被招募为二人组（对），其中包括一个PWD/MCI和一个CG。试验性研究共招募了10对二人组，其中5对二人组被分配到常规护理对照组，5对二人组参与舞蹈干预。干预组每周开会两次，每次60分钟，持续8周。主要结果是使用阿尔茨海默病生活质量（QoL-AD）问卷评估的出勤率和生活质量。次要结果包括通过功能磁共振成像（fMRI）的图论分析评估的平衡，情绪和大脑网络连接。课堂出勤率为96%，定性反馈反映了参与者与小组的社会联系。观察到生活质量和平衡的增加，但没有情绪。大脑成像分析显示，多个大脑网络特征增加，包括全局效率和模块化。将根据完整的临床试验数据进一步研究这种舞蹈干预对成像和非成像指标的积极影响。试验结果预计将于2022年夏季公布。
Alzheimer's disease has profound effects on quality of life, affecting not only cognition, but mobility and opportunities for social engagement. Dance is a form of movement that may be uniquely suited to help maintain quality of life for older adults, including those with dementia, because it inherently incorporates movement, social engagement, and cognitive stimulation. Here, we describe the methods and results of the pilot study for the IMOVE trial (NCT03333837, www.clinicaltrials.gov), a clinical trial designed to use improvisational dance classes to test the effects of movement and social engagement in people with mild cognitive impairment (MCI) or early-stage dementia. The pilot study was an 8-week investigation into the feasibility and potential effects of an improvisational dance intervention on people with MCI or early-stage dementia (PWD/MCI) and their caregivers (CG). The pilot aimed to assess changes in quality of life, balance, mood, and functional brain networks in PWD/MCI and their CG. Participants were recruited as dyads (pairs) that included one PWD/MCI and one CG. Ten total dyads were enrolled in the pilot study with five dyads assigned to the usual care control group and five dyads participating in the dance intervention. The intervention arm met twice weekly for 60 min for 8 weeks. Attendance and quality of life assessed with the Quality of Life in Alzheimer's disease (QoL-AD) questionnaire were the primary outcomes. Secondary outcomes included balance, mood and brain network connectivity assessed through graph theory analysis of functional magnetic resonance imaging (fMRI). Class attendance was 96% and qualitative feedback reflected participants felt socially connected to the group. Increases in quality of life and balance were observed, but not mood. Brain imaging analysis showed increases in multiple brain network characteristics, including global efficiency and modularity. Further investigation into the positive effects of this dance intervention on both imaging and non-imaging metrics will be carried out on the full clinical trial data. Results from the trial are expected in the summer of 2022.
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影响因子：
9.9
作者：
Cummings, JL
通讯作者：
Cummings, JL
影响因子：
4.3
作者：
Achard S;Bullmore E
通讯作者：
Bullmore E
影响因子：
4.8
作者：
Baniqued PL;Gallen CL;Voss MW;Burzynska AZ;Wong CN;Cooke GE;Duffy K;Fanning J;Ehlers DK;Salerno EA;Aguiñaga S;McAuley E;Kramer AF;D'Esposito M
通讯作者：
D'Esposito M
影响因子：
3.8
作者：
Cardaciotto, LeeAnn;Herbert, James D.;Farrow, Victoria
通讯作者：
Farrow, Victoria
DOI：
10.1073/pnas.1015950108
发表时间：
2011-02-15
影响因子：
11.1
作者：
Erickson, Kirk I.;Voss, Michelle W.;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.