Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform.
Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform.
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DOI:
10.1021/nl801958b
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发表时间:
2008-11
期刊:
影响因子:
10.8
通讯作者:
Mulder WJ
中科院分区:
文献类型:
--
作者:
Cormode DP;Skajaa T;van Schooneveld MM;Koole R;Jarzyna P;Lobatto ME;Calcagno C;Barazza A;Gordon RE;Zanzonico P;Fisher EA;Fayad ZA;Mulder WJ
High density lipoprotein (HDL), is an important natural nanoparticle that may be modified for biomedical imaging purposes. Here we developed a novel technique to create unique multimodality HDL mimicking nanoparticles by inclusion of gold, iron oxide or quantum dot nanocrystals for computed tomography, magnetic resonance and fluorescence imaging, respectively. By including additional labels in the corona of the particles, they were made multi-functional. The characterization of these nanoparticles, as well as their in vitro and in vivo behavior revealed that they closely mimic native HDL.
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影响因子:
10.8
作者:
Frias, Juan C.;Ma, Yanqing;Fisher, Edward A.
通讯作者:
Fisher, Edward A.
影响因子:
10.8
作者:
Huang, Xinlei;Bronstein, Lyudmila M.;Dragnea, Bogdan
通讯作者:
Dragnea, Bogdan
DOI:
10.1016/0005-2736(91)90246-5
发表时间:
1991-07-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子:
--
作者:
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通讯作者:
YAUYOUNG, A
影响因子:
10.8
作者:
El-Sayed, IH;Huang, XH;El-Sayed, MA
通讯作者:
El-Sayed, MA
影响因子:
15.9
作者:
HAVEL, RJ;EDER, HA;BRAGDON, JH
通讯作者:
BRAGDON, JH