Deterioration of sexual function is associated with central hemodynamics in adult Japanese men
Deterioration of sexual function is associated with central hemodynamics in adult Japanese men
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日本成年男性性功能恶化与中枢血流动力学有关
DOI：
10.1038/s41440-019-0336-1
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发表时间：
2019
影响因子：
5.4
通讯作者：
Maeda Seiji
中科院分区：
文献类型：
--
作者：
Kumagai Hiroshi;Yoshikawa Toru;Kosaki Keisei;Myoenzono Kanae;Maeda Seiji
主动脉血压升高比肱动脉血压升高与心血管疾病（CVD）的发病更密切相关。另一方面，勃起功能障碍（艾德）是一种外周血管功能障碍，也与CVD相关;然而，主动脉血压和艾德之间的关联尚未阐明。因此，我们的目的是调查成年男性艾德严重程度与主动脉血压之间的关系。在253名日本成年男性（59 ± 16岁）中，测量了主动脉（使用广义传递函数估计）和外周血流动力学。通过问卷调查（国际勃起功能指数5：IIEF 5）评估勃起功能，并根据IIEF 5评分将参与者分为三组（无艾德、轻度至中度艾德和中度至重度艾德）。中度至重度艾德患者的主动脉收缩压（SBP）和脉压（PP）显著高于无艾德或轻度至中度ED患者。此外，艾德的严重程度与反射时间、增强压力和增强指数显著相关。多变量线性回归分析表明，在考虑混杂因素后，中重度艾德与主动脉SBP和PP显著相关（分别为β= 0.129;p= 0.047，β= 0.165;p= 0.013），但与肱动脉SBP或PP无关。这些结果表明，中度至重度艾德与主动脉血压升高有关，因为反射波提前到达，并且是日本男性主动脉血压升高的独立预测因素。
Elevated aortic blood pressure is more strongly related to the onset of cardiovascular disease (CVD) than elevated brachial blood pressure. On the other hand, erectile dysfunction (ED) is a peripheral vascular disfunction and is also associated with CVD; however, the association between aortic blood pressure and ED has not yet been clarified. Therefore, we aimed to investigate the association between ED severity and aortic blood pressure in adult men. In 253 Japanese adult men (59 ± 16 years), aortic (estimated using a generalized transfer function) and peripheral hemodynamics were measured. Erectile function was assessed with a questionnaire (the International Index of Erectile Function 5: IIEF5), and participants were stratified into three groups based on the IIEF5 score (no ED, mild-to-moderate ED, and moderate-to-severe ED). Aortic systolic blood pressure (SBP) and pulse pressure (PP) were significantly higher in subjects with moderate-to-severe ED than in subjects with no ED or mild-to-moderate ED. In addition, the severity of ED was significantly associated with the time to reflection, augmentation pressure, and augmentation index. Multivariate linear regression analyses suggested that moderate-to-severe ED was significantly associated with aortic SBP and PP (β= 0.129;p= 0.047,β= 0.165;p= 0.013, respectively) but not brachial SBP or PP, after confounding factors were considered. These results suggest that moderate-to-severe ED is associated with elevated aortic blood pressure due to an earlier arrival of the reflected wave and is an independent predictor of elevated aortic blood pressure in Japanese men.
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无创中心收缩压（而非外周收缩压）独立预测中国社区人群颈动脉内膜中层厚度的进展
影响因子：
5.4
作者：
Pengfei Sun;Ying Yang;Guanliang Cheng;F. Fan;L. Qi;Lan Gao;Xiaoning Han;J. Jia;Y. Huo;Yan Zhang
通讯作者：
Yan Zhang
老年男性诊所的自我转诊患者：不仅仅是雄激素缺乏
DOI：
10.1080/tam.6.3.157.165
发表时间：
2003
期刊：
The Aging Male
影响因子：
--
作者：
Guy T'sjoen;Els Feyen;P. D. Kuyper;Frank Comhaire;Jean Kaufman
通讯作者：
Jean Kaufman
阻力训练引起的中央动脉顺应性降低与健康年轻男性心内膜下存活率降低相关。
DOI：
10.1139/apnm-2017-0449
发表时间：
2018
期刊：
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
影响因子：
--
作者：
Kaname Tagawa;Youngju Choi;Song;Toru Yoshikawa;Hiroshi Kumagai;S. Maeda
通讯作者：
S. Maeda
影响因子：
2.6
作者：
Okamura, K;Ando, F;Shimokata, H
通讯作者：
Shimokata, H
高血压合并勃起功能障碍患者的动脉功能和内膜中层厚度
影响因子：
4.9
作者：
C. Vlachopoulos;K. Aznaouridis;N. Ioakeimidis;K. Rokkas;D. Tsekoura;C. Vasiliadou;Elli Stefanadi;A. Askitis;C. Stefanadis
通讯作者：
C. Stefanadis