Q&A: What are pathogens, and what have they done to and for us?
Q&A: What are pathogens, and what have they done to and for us?
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DOI：
10.1186/s12915-017-0433-z
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发表时间：
2017-10-19
期刊：
影响因子：
5.4
通讯作者：
van Dorp L
中科院分区：
文献类型：
--
作者：
Balloux F;van Dorp L
微生物存在于我们身上、我们体内和我们周围。它们几乎栖息在地球上的每一个环境中，而普通人携带的细菌(主要是在肠道中)的数量超过了人类细胞。绝大多数微生物对我们无害，许多微生物对植物、动物和人类的健康都起着至关重要的作用。然而，其他病原体要么是专性的，要么是兼性的，对宿主产生一系列有害影响。直到最近，传染病一直是人类最常见的死亡原因，远远超过战争或饥荒造成的死亡人数。从人类诞生之日起，纵观整个历史，传染病塑造了人类的进化、人口学、移民和历史。
Microbes are found on us, within us and around us. They inhabit virtually every environment on the planet and the bacteria carried by an average human, mostly in their gut, outnumber human cells. The vast majority of microbes are harmless to us, and many play essential roles in plant, animal and human health. Others, however, are either obligate or facultative pathogens exerting a spectrum of deleterious effects on their hosts. Infectious diseases have historically represented the most common cause of death in humans until recently, exceeding by far the toll taken by wars or famines. From the dawn of humanity and throughout history, infectious diseases have shaped human evolution, demography, migrations and history.
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DOI：
10.1126/science.aaf5036
发表时间：
2016-04-15
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Faria NR;Azevedo RDSDS;Kraemer MUG;Souza R;Cunha MS;Hill SC;Thézé J;Bonsall MB;Bowden TA;Rissanen I;Rocco IM;Nogueira JS;Maeda AY;Vasami FGDS;Macedo FLL;Suzuki A;Rodrigues SG;Cruz ACR;Nunes BT;Medeiros DBA;Rodrigues DSG;Queiroz ALN;da Silva EVP;Henriques DF;da Rosa EST;de Oliveira CS;Martins LC;Vasconcelos HB;Casseb LMN;Simith DB;Messina JP;Abade L;Lourenço J;Alcantara LCJ;de Lima MM;Giovanetti M;Hay SI;de Oliveira RS;Lemos PDS;de Oliveira LF;de Lima CPS;da Silva SP;de Vasconcelos JM;Franco L;Cardoso JF;Vianez-Júnior JLDSG;Mir D;Bello G;Delatorre E;Khan K;Creatore M;Coelho GE;de Oliveira WK;Tesh R;Pybus OG;Nunes MRT;Vasconcelos PFC
通讯作者：
Vasconcelos PFC
影响因子：
64.8
作者：
Bos KI;Harkins KM;Herbig A;Coscolla M;Weber N;Comas I;Forrest SA;Bryant JM;Harris SR;Schuenemann VJ;Campbell TJ;Majander K;Wilbur AK;Guichon RA;Wolfe Steadman DL;Cook DC;Niemann S;Behr MA;Zumarraga M;Bastida R;Huson D;Nieselt K;Young D;Parkhill J;Buikstra JE;Gagneux S;Stone AC;Krause J
通讯作者：
Krause J
DOI：
10.1073/pnas.1611283113
发表时间：
2016-11-29
影响因子：
11.1
作者：
Eldholm, Vegard;Pettersson, John H. -O.;Balloux, Francois
通讯作者：
Balloux, Francois
影响因子：
6.4
作者：
Morens, David M.;Fauci, Anthony S.
通讯作者：
Fauci, Anthony S.
DOI：
10.1126/science.1213362
发表时间：
2012-06-22
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Herfst S;Schrauwen EJ;Linster M;Chutinimitkul S;de Wit E;Munster VJ;Sorrell EM;Bestebroer TM;Burke DF;Smith DJ;Rimmelzwaan GF;Osterhaus AD;Fouchier RA
通讯作者：
Fouchier RA