Cell surface- and rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis.
Cell surface- and rho GTPase-based auxin signaling controls cellular interdigitation in Arabidopsis.
复制标题
DOI：
10.1016/j.cell.2010.09.003
复制
发表时间：
2010-10-01
期刊：
影响因子：
64.5
通讯作者：
Yang Z
中科院分区：
文献类型：
--
作者：
Xu T;Wen M;Nagawa S;Fu Y;Chen JG;Wu MJ;Perrot-Rechenmann C;Friml J;Jones AM;Yang Z
生长素是植物生长发育和模式形成所必需的多功能激素。控制生长素诱导的基因表达的核生长素信号系统已经建立，但细胞质生长素信号系统在协调细胞极化方面尚未探索。我们发现了一种细胞质生长素信号传导机制，它调节拟南芥叶表皮铺面细胞（PC）的叉指状生长，这种细胞发育成叉指状的裂片和凹痕，在二维平面上形成拼图形状。在生长素生物合成或由位于叶尖的PINFORMED 1介导的生长素输出缺陷的叶中，PC交错是受损的。生长素协同激活两种Rho GTP酶R0P2和R0P6，其分别促进互补叶和凹陷的形成。生长素对这些ROP的激活在30秒内发生，并依赖于生长素结合蛋白1。这些发现揭示了基于Rho GTP酶的新的生长素信号传导机制，其调节跨细胞场的细胞扩展的空间协调。
Auxin is a multi-functional hormone essential for plant development and pattern formation. A nuclear auxin signaling system controlling auxin-induced gene expression is well established, but cytoplasmic auxin signaling as in its coordination of cell polarization is unexplored. We found a cytoplasmic auxin signaling mechanism that modulates the interdigitated growth of Arabidopsis leaf epidermal pavement cells (PCs), which develop interdigitated lobes and indentations to form a puzzle-piece shape in a two-dimensional plane. PC interdigitation is compromised in leaves deficient in either auxin biosynthesis or its export mediated by PINFORMED 1 localized at the lobe tip. Auxin coordinately activates two Rho GTPases, ROP2 and ROP6, which promote the formation of complementary lobes and indentations, respectively. Activation of these ROPs by auxin occurs within 30 seconds and depends on AUXIN-BINDING PROTEIN 1. These findings reveal Rho GTPase-based novel auxin signaling mechanisms, which modulate the spatial coordination of cell expansion across a field of cells.
登录
查看更多内容
DOI：
10.1016/j.cub.2009.08.052
发表时间：
2009-11-17
期刊：
Current biology : CB
影响因子：
--
作者：
Fu Y;Xu T;Zhu L;Wen M;Yang Z
通讯作者：
Yang Z
影响因子：
9.8
作者：
Hazak O;Bloch D;Poraty L;Sternberg H;Zhang J;Friml J;Yalovsky S
通讯作者：
Yalovsky S
影响因子：
10.5
作者：
Chen, JG;Ullah, H;Jones, AM
通讯作者：
Jones, AM
影响因子：
56.9
作者：
Jones, AM;Im, KH;Binns, AN
通讯作者：
Binns, AN
影响因子：
64.8
作者：
Dhonukshe, Pankaj;Tanaka, Hirokazu;Goh, Tatsuaki;Ebine, Kazuo;Mahonen, Ari Pekka;Prasad, Kalika;Blilou, Ikram;Geldner, Niko;Xu, Jian;Uemura, Tomohiro;Chory, Joanne;Ueda, Takashi;Nakano, Akihiko;Scheres, Ben;Friml, Jiri
通讯作者：
Friml, Jiri