The transmissibility and control of pandemic influenza A (H1N1) virus.
The transmissibility and control of pandemic influenza A (H1N1) virus.
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DOI:
10.1126/science.1177373
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发表时间:
2009-10-30
期刊:
影响因子:
--
通讯作者:
Longini IM Jr
中科院分区:
文献类型:
--
作者:
Yang Y;Sugimoto JD;Halloran ME;Basta NE;Chao DL;Matrajt L;Potter G;Kenah E;Longini IM Jr
Pandemic influenza A (H1N1) 2009 (pandemic H1N1) is spreading throughout the planet. It has become the dominant strain in the southern hemisphere, where the influenza season is underway. Here, based on reported case clusters in the USA, we estimate the household secondary attack rate for pandemic H1N1 to be 27.3% (95% CI: 12.2%–50.5%). From a school outbreak, we estimate a school child infects 2.4 (95% CI: 1.8–3.2) other children within the school. We estimate the basic reproductive number, R0, to range from 1.3–1.7 and the generation interval to range from 2.6–3.2 days. We use a simulation model to evaluate the effectiveness of vaccination strategies in the USA for the Fall, 2009. If vaccine were available soon enough, vaccination of children, followed by adults, reaching 70% overall coverage, in addition to high risk and essential workforce groups, could mitigate a severe epidemic.
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影响因子:
4.3
作者:
LONGINI, IM;ACKERMAN, E;ELVEBACK, LR
通讯作者:
ELVEBACK, LR
影响因子:
64.8
作者:
Mills CE;Robins JM;Lipsitch M
通讯作者:
Lipsitch M
影响因子:
4.2
作者:
Chowell, G.;Miller, M. A.;Viboud, C.
通讯作者:
Viboud, C.
DOI:
10.1073/pnas.0706849105
发表时间:
2008-03-25
影响因子:
11.1
作者:
Halloran, M. Elizabeth;Ferguson, Neil M.;Cooley, Philip
通讯作者:
Cooley, Philip
影响因子:
--
作者:
DUNN, FL;CAREY, DE;MARTIN, JD
通讯作者:
MARTIN, JD