'Silent' mitral cells dominate odor responses in the olfactory bulb of awake mice.

'Silent' mitral cells dominate odor responses in the olfactory bulb of awake mice.
复制标题

DOI:
10.1038/nn.3768
复制
发表时间:
2014-10
影响因子:
25
通讯作者:
Schaefer, Andreas T.
Schaefer, Andreas T.
中科院分区:
医学1区
文献类型:
--
作者:
Kollo, Mihaly;Schmaltz, Anja;Abdelhamid, Mostafa;Fukunaga, Izumi;Schaefer, Andreas T.

文献摘要

参考文献

被引文献

相似文献

清醒如何塑造神经活动是一个激烈讨论的话题;在清醒的嗅球中,在二尖瓣/簇状细胞(M/TC)中报告了具有弱感觉诱发反应的高活动。使用盲全细胞记录,我们发现33%的M/TC是“沉默的”,但表现出强烈的感觉反应-在“活跃”的神经元中有微弱或抑制性反应。因此,以前错过的M/TC亚群可以对嗅球产生强大的影响。
How wakefulness shapes neural activity is a topic of intense discussion; in the awake olfactory bulb, high activity with weak sensory-evoked responses were reported in mitral/tufted cells (M/TCs). Using blind whole-cell recordings, we find 33% of M/TCs to be “silent”, yet showing strong sensory responses - with weak or inhibitory responses in “active” neurons. Thus, a previously missed M/TC subpopulation can exert powerful influence over the olfactory bulb.
DOI: 10.1038/nature11665
发表时间: 2013-01-03
期刊: Nature
影响因子: 64.8
作者:
通讯作者: --
DOI: 10.1023/a:1008819818970
发表时间: 1997-07-01
影响因子: 1.2
作者:
Bhalla, US;Bower, JM
通讯作者: Bower, JM
DOI: 10.1152/jn.91019.2008
发表时间: 2009-04-01
影响因子: 2.5
作者:
Matsumoto, Hideyuki;Kashiwadani, Hideki;Mori, Kensaku
通讯作者: Mori, Kensaku
DOI: 10.1016/j.neuron.2012.09.037
发表时间: 2012-12-06
期刊: Neuron
影响因子: 16.2
作者:
Kato HK;Chu MW;Isaacson JS;Komiyama T
通讯作者: Komiyama T
DOI: 10.1523/jneurosci.0884-06.2006
发表时间: 2006-08-23
影响因子: 5.3
作者:
Rinberg, Dmitry;Koulakov, Alex;Gelperin, Alan
通讯作者: Gelperin, Alan