Classic Kaposi's sarcoma in Italy, 1985-1998.

Classic Kaposi's sarcoma in Italy, 1985-1998.
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DOI:
10.1038/sj.bjc.6602265
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发表时间:
2005-01-17
影响因子:
8.8
通讯作者:
--
中科院分区:
医学1区
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--
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为了评估经典卡波西肉瘤(CKS)在艾滋病传播后在意大利的发病率(IRS),我们使用15个癌症登记处(CRS)(占意大利人口的21%)和国家艾滋病登记处之间的“特别”记录联系程序,将CKS与艾滋病相关KS(AKS)区分开来。1985~1998年间,共确诊874例CKS和634例AKS。在55岁以下的KS病例中,男性和女性的CKS分别占16%和27%,但在55岁以上的KS病例中,CKS分别占91%和100%。 指数男性为1/10,女性为1/100,但男性在翁布里亚为0.3,萨萨里为4.7,女性在帕尔玛为0.1,萨萨里为1.7。1985-1987和1993-1998年间,CKS男女儿童的IRS均保持稳定。在北部和中部CRS,出生在同一地区的人的CKS的IR(经年龄和性别调整)为0.5,而在意大利南部或群岛出生的人的IR为1.6(比率=3.2),这表明KS相关的疱疹病毒,即KS的病因,是在生命早期获得的。
To evaluate incidence rates (IRs) of classic Kaposi's sarcoma (CKS) in Italy after the spread of AIDS, we distinguished CKS from AIDS-related KS (AKS) using an ‘ad hoc’ record linkage procedure between 15 Cancer Registries (CRs) (21% of the Italian population) and the national AIDS Registry. Between 1985 and 1998, 874 cases of CKS and 634 cases of AKS were diagnosed in the study areas. CKS accounted for 16 and 27% of KS cases below 55 years of age in men and women, respectively, but for 91 and 100% of those above age 55. The IRs for CKS were 1.0/ in men and 0.4/100 000 in women, but they varied between 0.3 in Umbria and 4.7 in Sassari in men, and between 0.1 in Parma and 1.7 in Sassari in women. IRs of CKS in both genders were stable between 1985–1987 and 1993–1998. In Northern and Central CRs the IR (adjusted for age and gender) for CKS was 0.5 in individuals born in the same area, but 1.6 in individuals born in Southern Italy or in the Islands (rate ratio=3.2) suggesting that KS-associated herpesvirus, the cause of KS, is acquired early in life.
DOI: 10.1038/bjc.1994.60
发表时间: 1994-02
影响因子: 8.8
作者:
Geddes, M;Franceschi, S;Barchielli, A;Falcini, F;Carli, S;Cocconi, G;Conti, E;Crosignani, P;Gafa, L;Giarelli, L
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发表时间: 2003-12-01
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发表时间: 1988-09-15
影响因子: 6.4
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通讯作者: ATTEWELL, R
DOI: 10.1177/030089169508100502
发表时间: 1995-09-01
期刊: TUMORI
影响因子: --
作者:
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通讯作者: Geddes, M