Aerobic reserve capacity in multiple sclerosis-Preliminary evidence.
Aerobic reserve capacity in multiple sclerosis-Preliminary evidence.
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DOI：
10.1111/ane.13441
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发表时间：
2021-09
影响因子：
3.5
通讯作者：
Motl, Robert W.
中科院分区：
文献类型：
--
作者：
Feasel, Corey D.;Sandroff, Brian M.;Motl, Robert W.
有氧储备能力反映了执行日常生活任务的可用能量，并在老年人中进行了研究。这项初步研究检验了多发性硬化症（MS）中有氧储备能力的概念和测量的证据。21名完全活动的多发性硬化症患者进行了最大心肺运动试验（CPET）。我们根据峰值有氧功率（VO2peak）和第一阶段耗氧量（VO2）的差异计算有氧储备能力。参与者完成了残疾评估（扩展残疾状态量表，EDSS）、认知（符号数字模式测试，SDMT）、情绪（贝克抑郁量表，BDI）、步行耐力（6分钟步行距离，6MWD）、步行速度（20英尺步行时间，T25FW）、多发性硬化症影响量表，MSIS-29)和人体测量（身高和体重）。有氧储备容量为9.3±3.7 ml/kg/min。有氧储备能力与VO2peak （ρ = 0.67, p < 0.01）、精疲力竭时间（ρ = 0.63, p < 0.01）和SDMT （ρ = 0.51, p < 0.05）呈正相关。有氧储备能力与BMI呈负相关（ρ = -）。62, p < 0.01)和RHR （ρ = - 0.47, p < 0.05）。我们提供了初步证据，表明有氧储备能力是ms患者最大CPET（例如，修改的Balke方案）得出的一个可行结果。有氧储备能力与临床相关结果相关，并可能成为未来研究中康复的重要结果。
Aerobic reserve capacity reflects the available energy for performing everyday life tasks, and it has been studied in older adult populations. This preliminary study examined proof of concept and measurement of aerobic reserve capacity in multiple sclerosis (MS). Twenty-one fully ambulatory people with MS performed a maximal, cardiopulmonary exercise test (CPET). We calculated aerobic reserve capacity based on the difference peak aerobic power (VO2peak) and first stage oxygen consumption (VO2). Participants completed assessments for disability (Expanded Disability Status Scale, EDSS), cognition (Symbol Digit Modalities Test, SDMT), mood (Beck Depression Inventory, BDI), walking endurance (six-minute walk distance, 6MWD), walking speed (Timed Twenty-Foot Walk, T25FW), impact of MS (Multiple Sclerosis Impact Scale, MSIS-29), and anthropometric measurements (height and weight). Aerobic reserve capacity was 9.3 ± 3.7 ml/kg/min. Aerobic reserve capacity was positively associated with VO2peak (ρ = .67, p < .01), time to exhaustion (ρ = .63, p < .01), and SDMT (ρ = .51, p < .05). Aerobic reserve capacity was negatively associated with BMI (ρ = −.62, p < .01) and RHR (ρ = −0.47, p < .05). We provide preliminary evidence that aerobic reserve capacity is a feasible outcome derived from maximal CPET (eg, modified Balke protocol) in MS. Aerobic reserve capacity was associated with clinically relevant outcomes and could become an important outcome for rehabilitation in future research.
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影响因子：
2.9
作者：
Prakash RS;Snook EM;Motl RW;Kramer AF
通讯作者：
Kramer AF
DOI：
10.1249/00005768-198205000-00012
发表时间：
1982-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
BORG, GAV
通讯作者：
BORG, GAV
影响因子：
9.9
作者：
RAO, SM;LEO, GJ;UNVERZAGT, F
通讯作者：
UNVERZAGT, F
影响因子：
9.8
作者：
Klaren, Rachel E.;Sandroff, Brian M.;Motl, Robert W.
通讯作者：
Motl, Robert W.
DOI：
10.1164/arrd.1986.134.5.1005
发表时间：
1986-11-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
OLGIATI, R;JACQUET, J;DIPRAMPERO, PE
通讯作者：
DIPRAMPERO, PE