Importance of physical evaluation using skeletal muscle mass index and body fat percentage to prevent sarcopenia in elderly Japanese diabetes patients.
Importance of physical evaluation using skeletal muscle mass index and body fat percentage to prevent sarcopenia in elderly Japanese diabetes patients.
复制标题
使用骨骼肌质量指数和体内脂肪百分比进行物理评估的重要性，以防止日本老年糖尿病患者的肌肉减少症。
DOI：
10.1111/jdi.12908
复制
发表时间：
2019-03
影响因子：
3.2
通讯作者：
Yamada Y
中科院分区：
文献类型：
--
作者：
Fukuoka Y;Narita T;Fujita H;Morii T;Sato T;Sassa MH;Yamada Y
探讨老年糖尿病患者肌肉减少症的患病率、相关因素及体质评价指标。这是一项横断面观察研究。本研究共招募了267名年龄>65岁的糖尿病患者（159名男性，108名女性）。根据亚洲肌肉减少症工作组的标准，测量骨骼肌质量指数、握力和通常的步态速度以诊断肌肉减少症。使用生物电阻抗分析测量身体组成。以四分位数评价体重指数（BMI）和体脂百分比，以探讨与肌肉减少症的关系。多元逻辑回归分析检查了肌肉减少症相关因素。所有参与者中肌肉减少症的患病率为18.7%，并随年龄增长而增加。随着BMI的增加，肌肉减少症减少（P < 0.01，Cochran-Armitage检验）。相反，第三四分位体脂肪百分比组显示出最低的肌肉减少症患病率。体质量与骨骼肌质量指数呈显著正相关（R = 0.702-0.682）。多因素Logistic回归分析显示，男性肌肉减少症与较低的BMI、未使用二甲双胍和较低的骨矿物质含量相关（P < 0.05），女性与较低的骨矿物质含量、较低的血清白蛋白水平和年龄较大相关（P < 0.05）。目前的研究表明，除了低BMI之外，高体脂百分比的糖尿病患者可能会发生肌肉减少症。建议对老年糖尿病患者进行以BMI和体脂百分比为评价指标的身体管理，预防肌肉减少症的发生。
To investigate the prevalence of sarcopenia, its related factors and indicators of physical evaluation in elderly diabetes patients. This was a cross‐sectional observation study. A total of 267 diabetes patients (159 men, 108 women) aged >65 years were recruited in the present study. Skeletal muscle mass index, grip strength and usual gait speed were measured to diagnose sarcopenia according to the Asian Working Group for Sarcopenia. Body composition was measured using bioelectrical impedance analysis. Body mass index (BMI) and body fat percentage were evaluated in quartiles to investigate the relationship with sarcopenia. A multiple logistic regression analysis examined sarcopenia‐related factors. The prevalence of sarcopenia in all participants was 18.7% and increased with age. Sarcopenia decreased as BMI increased (P < 0.01, Cochran–Armitage test). In contrast, the third quartile body fat percentage group showed the lowest prevalence of sarcopenia. A strong positive correlation was observed between body mass and skeletal muscle mass indices (R = 0.702–0.682). Multiple logistic regression analysis showed that sarcopenia was associated with lower BMI, non‐use of metformin and lower bone mineral content in men (P < 0.05), and lower bone mineral content, lower serum levels of albumin and older age in women (P < 0.05). The present study suggests that diabetes patients with a high body fat percentage in addition to low BMI might develop sarcopenia. It is suggested that physical management in elderly diabetes patients should be carried out based on the evaluation of BMI and body fat percentage to prevent sarcopenia.
登录
查看更多内容
影响因子：
6.3
作者：
Solini, Anna;Penno, Giuseppe;Pugliese, Giuseppe
通讯作者：
Pugliese, Giuseppe
影响因子：
1.6
作者：
Makanae, Yuhei;Fujita, Satoshi
通讯作者：
Fujita, Satoshi
DOI：
10.1093/gerona/glu023
发表时间：
2014-05-01
影响因子：
5.1
作者：
Cawthon, Peggy M.;Peters, Katherine W.;Alley, Dawn E.
通讯作者：
Alley, Dawn E.
影响因子：
16.2
作者：
Park, Seok Won;Goodpaster, Bret H.;Newman, Anne B.
通讯作者：
Newman, Anne B.
影响因子：
7.7
作者：
Park, Seok Won;Goodpaster, Bret H.;Newman, Anne B.
通讯作者：
Newman, Anne B.