The Influence of the Head Model Conductor on the Source Localization of Auditory Evoked Potentials.
The Influence of the Head Model Conductor on the Source Localization of Auditory Evoked Potentials.
复制标题
头部模型导体对听觉源源的影响诱发电位的影响。
DOI：
10.1007/s10548-021-00871-z
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发表时间：
2021-11
期刊：
影响因子：
2.7
通讯作者：
Richards JE
中科院分区：
文献类型：
--
作者：
Conte S;Richards JE
当对真实的头部体积导体进行建模时，脑电图源分析重建的准确性会提高。在这项研究中，我们研究了逐渐复杂的头部表征如何影响听觉诱发电位（AEP）的空间定位。十四名听力正常的年轻成人参与者执行了 AEP 任务。个体化头部模型是通过在单独的会议中收集的结构 MRI 和扩散加权成像 (DWI) 扫描获得的。在被动聆听的强直范式中，AEP 是由 1k Hz 和 4k Hz 突发音调引发的。我们比较了用 1k Hz 声音进行 4 分钟强直刺激前后 N1 和 P2 分量的幅度。在初级听觉皮层和邻近区域研究了这两种成分的电流密度重建（CDR）值。此外，我们还比较了 EEG 正向解中 10 个不同头部模型获得的信号拓扑和幅度。从最简单的模型（头皮、头骨、大脑）开始，我们研究了 CSF 建模、区分 GM 和 WM 导体以及包括各向异性 WM 值的影响。我们将 AEP 的活动定位在初级听觉皮层内，但不在邻近区域。脑脊液室的包含对源重建的影响最大，而白质各向异性的改善较小。我们的结论是，在对 CSF 导体进行建模时，个性化的真实头部模型为正向解决方案提供了最佳解决方案。
The accuracy of EEG source analysis reconstruction improves when a realistic head volume conductor is modeled. In this study we investigated how the progressively more complex head representations influence the spatial localization of auditory-evoked potentials (AEPs). Fourteen young-adult participants with normal hearing performed the AEP task. Individualized head models were obtained from structural MRI and diffusion-weighted imaging (DWI) scans collected in a separate session. AEPs were elicited by 1k Hz and 4k Hz tone bursts during a passive-listening tetanizing paradigm. We compared the amplitude of the N1 and P2 components before and after 4 minutes of tetanic-stimulation with 1k Hz sounds. Current density reconstruction (CDR) values of both components were investigated in the primary auditory cortex and adjacent areas. Furthermore, we compared the signal topography and magnitude obtained with 10 different head models on the EEG forward solution. Starting from the simplest model (scalp, skull, brain), we investigated the influence of modeling the CSF, distinguishing between GM and WM conductors, and including anisotropic WM values. We localized the activity of AEPs within the primary auditory cortex, but not in adjacent areas. The inclusion of the CSF compartment had the strongest influence on the source reconstruction, whereas white matter anisotropy led to a smaller improvement. We conclude that individualized realistic head models provide the best solution for the forward solution when modeling the CSF conductor.
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影响因子：
3.7
作者：
Gao, Chuanji;Conte, Stefania;Hanayik, Taylor
通讯作者：
Hanayik, Taylor
影响因子：
3.7
作者：
Harris KC;Wilson S;Eckert MA;Dubno JR
通讯作者：
Dubno JR
影响因子：
3.4
作者：
Clapp, WC;Kirk, IJ;Teyler, TJ
通讯作者：
Teyler, TJ
影响因子：
5.7
作者：
Conte, Stefania;Richards, John E.;Roberts, Jane E.
通讯作者：
Roberts, Jane E.
DOI：
10.1016/j.clinph.2009.09.007
发表时间：
2009-12
期刊：
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
影响因子：
--
作者：
Lee WH;Liu Z;Mueller BA;Lim K;He B
通讯作者：
He B