Multidimensional processing in the amygdala.
Multidimensional processing in the amygdala.
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DOI:
10.1038/s41583-020-0350-y
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发表时间:
2020-10
期刊:
影响因子:
--
通讯作者:
Gothard KM
中科院分区:
文献类型:
--
作者:
Gothard KM
Brain-wide circuits that coordinate affective and social behaviours intersect in the amygdala. Consequently, amygdala lesions cause a heterogeneous array of social and non-social deficits. Social behaviours are not localized to subdivisions of the amygdala even though the inputs and outputs that carry social signals are anatomically restricted to distinct subnuclear regions. This observation may be explained by the multidimensional response properties of the component neurons. Indeed, the multitudes of circuits that converge in the amygdala enlist the same subset of neurons into different ensembles that combine social and non-social elements into high-dimensional representations. These representations may enable flexible, context-dependent social decisions. As such, multidimensional processing may operate in parallel with subcircuits of genetically identical neurons that serve specialized and functionally dissociable functions. When combined, the activity of specialized circuits may grant specificity to social behaviours, whereas multidimensional processing facilitates the flexibility and nuance needed for complex social behaviour.
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影响因子:
1.9
作者:
Bliss-Moreau E;Bauman MD;Amaral DG
通讯作者:
Amaral DG
影响因子:
16.6
作者:
Dal Monte O;Costa VD;Noble PL;Murray EA;Averbeck BB
通讯作者:
Averbeck BB
影响因子:
2.7
作者:
Bliss-Moreau E;Moadab G;Santistevan A;Amaral DG
通讯作者:
Amaral DG
影响因子:
16.2
作者:
Duvarci S;Pare D
通讯作者:
Pare D
DOI:
10.1037/h0077848
发表时间:
1981-01-01
期刊:
JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子:
--
作者:
AGGLETON, JP;PASSINGHAM, RE
通讯作者:
PASSINGHAM, RE