Daily sleep quality affects drug craving, partially through indirect associations with positive affect, in patients in treatment for nonmedical use of prescription drugs.
Daily sleep quality affects drug craving, partially through indirect associations with positive affect, in patients in treatment for nonmedical use of prescription drugs.
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DOI：
10.1016/j.addbeh.2016.08.026
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发表时间：
2017-02
影响因子：
4.4
通讯作者：
Bunce, Scott C.
中科院分区：
文献类型：
--
作者：
Lydon-Staley, David M.;Cleveland, H. Harrington;Huhn, Andrew S.;Cleveland, Michael J.;Harris, Jonathan;Stankoski, Dean;Deneke, Erin;Meyer, Roger E.;Bunce, Scott C.
睡眠障碍已被确定为一系列物质成瘾复发的一个风险因素。在关于处方药非医疗使用（NMUPD）的研究中，睡眠质量与治疗结果之间的关系相对较少受到关注。本研究考察了因治疗NMUPD而住院的医学戒毒患者中睡眠质量与渴望之间的个体内关联。
参与者（n = 68）平均在9.36天（标准差 = 2.99）内每天报告他们的睡眠质量、负面情绪（NA）、正面情绪（PA）和渴望情况。使用多层模型检验睡眠质量和渴望之间的个体内关联。使用个体内中介分析来评估NA和PA在睡眠质量与渴望之间关系中的中介作用。
在睡眠质量低于平常的日子里观察到更强烈的渴望（γ10 = -0.10，p = 0.003）。睡眠质量与渴望之间总体关联的31%可由PA解释，即睡眠质量较差与较低的PA相关，进而较低的PA与更强烈的渴望相关。没有证据表明睡眠质量通过NA与渴望存在间接关联。
睡眠质量的日常波动与渴望的波动相关，这种关联部分由睡眠质量与日常PA之间的关联所解释。这些数据鼓励进一步研究NMUPD患者以及其他物质使用障碍患者中睡眠、情绪和渴望之间的关系。
Sleep disturbance has been identified as a risk factor for relapse in addiction to a range of substances. The relationship between sleep quality and treatment outcome has received relatively little attention in research on nonmedical use of prescription drugs (NMUPD). This study examined the within-person association between sleep quality and craving in medically detoxified patients in residence for the treatment of NMUPD. Participants (n= 68) provided daily reports of their sleep quality, negative affect (NA), positive affect (PA), and craving for an average of 9.36 (SD= 2.99) days. Within-person associations of sleep quality and craving were examined using multilevel modeling. Within-person mediation analyses were used to evaluate the mediating roles of NA and PA in the relationship between sleep quality and craving. Greater cravings were observed on days of lower than usual sleep quality (γ10 = −0.10, p = .003). Thirty-one percent of the overall association between sleep quality and craving was explained by PA, such that poorer sleep quality was associated with lower PA and, in turn, lower PA was associated with greater craving. No evidence emerged for an indirect association between sleep quality and craving through NA. Daily fluctuations in sleep quality were associated with fluctuations in craving, an association partially explained by the association between sleep quality and daily PA. These data encourage further research on the relationship between sleep, affect, and craving in NMUPD patients, as well as in patients with other substance use disorders.
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影响因子：
2.3
作者：
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作者：
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