A novel Arabidopsis MYB-like transcription factor, MYBH, regulates hypocotyl elongation by enhancing auxin accumulation.
A novel Arabidopsis MYB-like transcription factor, MYBH, regulates hypocotyl elongation by enhancing auxin accumulation.
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DOI：
10.1093/jxb/ert223
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发表时间：
2013-09
影响因子：
6.9
通讯作者：
Lee H
中科院分区：
文献类型：
--
作者：
Kwon Y;Kim JH;Nguyen HN;Jikumaru Y;Kamiya Y;Hong SW;Lee H
对发育或环境刺激的关键反应由不同的转录因子介导，包括ERF、bZIP、MYB、MYC和WRKY家族的成员。其中，MYB基因在许多发育过程中发挥作用。MYB基因MYBH的过表达显著增加了光照条件下拟南芥下胚轴的伸长，且该基因在黑暗中的表达显著增强。MYBH蛋白含有一个保守的基序R/KLFGV，该基序与转录抑制有关。有趣的是，赤霉素生物合成抑制剂多效唑阻止了过量表达MYBH的幼苗下胚轴伸长的增加。此外，MYBH的功能依赖于光敏色素相互作用因子(PIF)蛋白。综上所述，这些结果表明，下胚轴的伸长受到一种微妙而有效的机制的调控，在这种机制中，MYBH的表达受到黑暗等环境条件的挑战，导致PIF的积累增加，从而促进生长素的生物合成。这些结果表明，MYBH是调节下胚轴伸长对黑暗反应的分子成分之一。
Critical responses to developmental or environmental stimuli are mediated by different transcription factors, including members of the ERF, bZIP, MYB, MYC, and WRKY families. Of these, MYB genes play roles in many developmental processes. The overexpression of one MYB gene, MYBH, significantly increased hypocotyl elongation in Arabidopsis thaliana plants grown in the light, and the expression of this gene increased markedly in the dark. The MYBH protein contains a conserved motif, R/KLFGV, which was implicated in transcriptional repression. Interestingly, the gibberellin biosynthesis inhibitor paclobutrazol blocked the increase in hypocotyl elongation in seedlings that overexpressed MYBH. Moreover, the function of MYBH was dependent on phytochrome-interacting factor (PIF) proteins. Taken together, these results suggest that hypocotyl elongation is regulated by a delicate and efficient mechanism in which MYBH expression is triggered by challenging environmental conditions such as darkness, leading to an increase in PIF accumulation and subsequent enhanced auxin biosynthesis. These results indicate that MYBH is one of the molecular components that regulate hypocotyl elongation in response to darkness.
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影响因子：
6.9
作者：
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通讯作者：
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影响因子：
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