Non-Invasive Blood Perfusion Measurements Using a Combined Temperature and Heat Flux Surface Probe.
Non-Invasive Blood Perfusion Measurements Using a Combined Temperature and Heat Flux Surface Probe.
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DOI：
10.1016/j.ijheatmasstransfer.2008.04.051
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发表时间：
2008-11-01
影响因子：
5.2
通讯作者：
Diller, Thomas E.
中科院分区：
文献类型：
--
作者：
Ricketts, Patricia L.;Mudaliar, Ashvinikumar V.;Ellis, Brent E.;Pullins, Clay A.;Meyers, Leah A.;Lanz, Otto I.;Scott, Elaine P.;Diller, Thomas E.
非侵入性血液灌注测量系统已经开发出来，并在体模组织和动物模型中进行测试。探头使用一个小型传感器，带有一个叠层平板热电偶，用于测量对施加在组织表面上的任意热事件（对流或传导）的热传递和温度响应。通过将热通量数据与组织的数学模型进行比较来估计血液灌注和热接触电阻。使用体模组织试验台和暴露大鼠肝脏试验评价灌注探头的可重复性和灵敏度。通过控制进入体模组织测试部分的水流来改变体模组织测试中的灌注，并且通过暂时阻塞通过门静脉的血流来改变暴露肝脏测试中的灌注。体模组织测试表明，探头可用于检测灌注的微小变化（0.005 ml/ml/s）。探头定性跟踪由于门静脉阻塞引起的肝脏模型灌注的变化。
Non-invasive blood perfusion measurement systems have been developed and tested in a phantom tissue and an animal model. The probes use a small sensor with a laminated flat thermocouple to measure the heat transfer and temperature response to an arbitrary thermal event (convective or conductive) imposed on the tissue surface. Blood perfusion and thermal contact resistance are estimated by comparing heat flux data with a mathematical model of the tissue. The perfusion probes were evaluated for repeatability and sensitivity using both a phantom tissue test stand and exposed rat liver tests. Perfusion in the phantom tissue tests was varied by controlling the flow of water into the phantom tissue test section, and the perfusion in the exposed liver tests was varied by temporarily occluding blood flow through the portal vein. The phantom tissue tests indicated that the probes can be used to detect small changes in perfusion (0.005 ml/ml/s). The probes qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein.
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影响因子：
3.1
作者：
Boellaard, R;Knaapen, P;Lammertsma, AA
通讯作者：
Lammertsma, AA
DOI：
10.1097/01.bcr.0000076091.79370.56
发表时间：
2003-07-01
期刊：
JOURNAL OF BURN CARE & REHABILITATION
影响因子：
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作者：
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通讯作者：
Hunt, JL
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作者：
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通讯作者：
Vallée, JP
影响因子：
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作者：
Oltean, M;Aneman, A;Herlenius, G
通讯作者：
Herlenius, G
影响因子：
3.8
作者：
CASTELLANA, FS;SKALAK, R;CASE, RB
通讯作者：
CASE, RB