Antigen presentation by Langerhans cells.
Antigen presentation by Langerhans cells.
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DOI:
10.1016/j.coi.2012.11.007
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发表时间:
2013-02
影响因子:
7
通讯作者:
Kaplan DH
中科院分区:
文献类型:
--
作者:
Igyártó BZ;Kaplan DH
Langerhans cells and other skin-resident dendritic cells (DC) are required for the development of cutaneous adaptive immune responses. In vivo experiments using mice with selective DC-subset deficiencies and ex vivo experiments using isolated DC suggests that each subset makes a unique contribution to the adaptive response. This review focuses on the functional outcome of antigen presentation by Langerhans cells. Special attention is given to their ability to promote CD4 T cell differentiation in a variety of inflammatory contexts and whether this subset has the capacity to cross-prime CD8 T cells.
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DOI:
10.4049/jimmunol.1001802
发表时间:
2010-10-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Bobr A;Olvera-Gomez I;Igyarto BZ;Haley KM;Hogquist KA;Kaplan DH
通讯作者:
Kaplan DH
DOI:
10.1038/jid.2009.343
发表时间:
2010-03
期刊:
The Journal of investigative dermatology
影响因子:
--
作者:
通讯作者:
--
影响因子:
32.4
作者:
Seneschal J;Clark RA;Gehad A;Baecher-Allan CM;Kupper TS
通讯作者:
Kupper TS
影响因子:
30.5
作者:
Bedoui, Sammy;Whitney, Paul G.;Heath, William R.
通讯作者:
Heath, William R.
影响因子:
6.5
作者:
ROMANI, N;LENZ, A;SCHULER, G
通讯作者:
SCHULER, G