Recognizing the Benefits of Pre-/Probiotics in Metabolic Syndrome and Type 2 Diabetes Mellitus Considering the Influence of Akkermansia muciniphila as a Key Gut Bacterium.
Recognizing the Benefits of Pre-/Probiotics in Metabolic Syndrome and Type 2 Diabetes Mellitus Considering the Influence of Akkermansia muciniphila as a Key Gut Bacterium.
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DOI：
10.3390/microorganisms9030618
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发表时间：
2021-03-17
期刊：
影响因子：
4.5
通讯作者：
Bungau S
中科院分区：
文献类型：
--
作者：
Corb Aron RA;Abid A;Vesa CM;Nechifor AC;Behl T;Ghitea TC;Munteanu MA;Fratila O;Andronie-Cioara FL;Toma MM;Bungau S
代谢综合征（MetS）和2型糖尿病（T2 DM）是受肠道微生物群结构影响的疾病，其改善在代谢病理学中常常被忽视。本文着重介绍了以下几个方面：益生菌/肠道微生物与代谢综合征发病机制的关系，补充嗜粘蛋白阿克曼氏菌在代谢综合征发病中的特殊积极作用，以及膳食多酚（益生元）与肠道菌群之间的相互作用。因此，对肠道微生物群与慢性代谢疾病之间经常被忽视的相关性进行了广泛而深入的分析，考虑到这一主题通过发现新菌株及其有益特性继续吸引和刺激研究人员。
Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are diseases that can be influenced by the structure of gut microbiota, whose improvement is often neglected in metabolic pathology. This review highlights the following main aspects: the relationship between probiotics/gut microbes with the pathogenesis of MetS, the particular positive roles of Akkermansia muciniphila supplementation in the onset of MetS, and the interaction between dietary polyphenols (prebiotics) with gut microbiota. Therefore, an extensive and in-depth analysis of the often-neglected correlation between gut microbiota and chronic metabolic diseases was conducted, considering that this topic continues to fascinate and stimulate researchers through the discovery of novel strains and their beneficial properties.
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影响因子：
4.4
作者：
Bernini, Luciana Jesus;Colado Simao, Andrea Name;Costa, Giselle Nobre
通讯作者：
Costa, Giselle Nobre
影响因子：
24.5
作者：
Cani PD
通讯作者：
Cani PD
影响因子：
4.6
作者：
Aoki R;Kamikado K;Suda W;Takii H;Mikami Y;Suganuma N;Hattori M;Koga Y
通讯作者：
Koga Y
DOI：
10.1126/science.aam9949
发表时间：
2017-08-11
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Byndloss MX;Olsan EE;Rivera-Chávez F;Tiffany CR;Cevallos SA;Lokken KL;Torres TP;Byndloss AJ;Faber F;Gao Y;Litvak Y;Lopez CA;Xu G;Napoli E;Giulivi C;Tsolis RM;Revzin A;Lebrilla CB;Bäumler AJ
通讯作者：
Bäumler AJ
影响因子：
8.2
作者：
Allin KH;Tremaroli V;Caesar R;Jensen BAH;Damgaard MTF;Bahl MI;Licht TR;Hansen TH;Nielsen T;Dantoft TM;Linneberg A;Jørgensen T;Vestergaard H;Kristiansen K;Franks PW;IMI-DIRECT consortium;Hansen T;Bäckhed F;Pedersen O
通讯作者：
Pedersen O