Comparative genome mapping of the deer mouse (Peromyscus maniculatus) reveals greater similarity to rat (Rattus norvegicus) than to the lab mouse (Mus musculus).
Comparative genome mapping of the deer mouse (Peromyscus maniculatus) reveals greater similarity to rat (Rattus norvegicus) than to the lab mouse (Mus musculus).
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DOI：
10.1186/1471-2148-8-65
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发表时间：
2008-02-26
影响因子：
3.4
通讯作者：
Dewey MJ
中科院分区：
文献类型：
--
作者：
Ramsdell CM;Lewandowski AA;Glenn JL;Vrana PB;O'Neill RJ;Dewey MJ
Deer mice (Peromyscus maniculatus) and congeneric species are the most common North American mammals. They represent an emerging system for the genetic analyses of the physiological and behavioral bases of habitat adaptation. Phylogenetic evidence suggests a much more ancient divergence of Peromyscus from laboratory mice (Mus) and rats (Rattus) than that separating latter two. Nevertheless, early karyotypic analyses of the three groups suggest Peromyscus to be exhibit greater similarities with Rattus than with Mus. Comparative linkage mapping of an estimated 35% of the deer mouse genome was done with respect to the Rattus and Mus genomes. We particularly focused on regions that span synteny breakpoint regions between the rat and mouse genomes. The linkage analysis revealed the Peromyscus genome to have a higher degree of synteny and gene order conservation with the Rattus genome. These data suggest that: 1. the Rattus and Peromyscus genomes more closely represent ancestral Muroid and rodent genomes than that of Mus. 2. the high level of genome rearrangement observed in Muroid rodents is especially pronounced in Mus. 3. evolution of genome organization can operate independently of more commonly assayed measures of genetic change (e.g. SNP frequency).
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影响因子：
30.8
作者：
Lyons, LA;Laughlin, TF;OBrien, SJ
通讯作者：
OBrien, SJ
影响因子：
2.5
作者：
Cavagna, P;Menotti, A;Stanyon, R
通讯作者：
Stanyon, R
影响因子：
2.5
作者：
Loschiavo, Maria;Nguyen, Quang K.;Vrana, Paul B.
通讯作者：
Vrana, Paul B.
影响因子：
3.1
作者：
Menotti-Raymond, M;David, VA;Murphy, WJ
通讯作者：
Murphy, WJ
影响因子：
56.9
作者：
Murphy, WJ;Larkin, DM;Lewin, HA
通讯作者：
Lewin, HA