Microbial telesensing: probing the environment for friends, foes, and food.

Microbial telesensing: probing the environment for friends, foes, and food.
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DOI:
10.1016/j.chom.2009.07.004
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发表时间:
2009-08-20
影响因子:
30.3
通讯作者:
Gilmore MS
Gilmore MS
中科院分区:
医学1区
文献类型:
--
作者:
Roux A;Payne SM;Gilmore MS

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细菌感应电路可能由来自环境的分子(例如,营养素、化学诱导剂)触发。细菌还积极探测环境中的信息,释放分子探测器来测量细胞表面以外的条件--遥感。感知外部环境是通过感知这些探针中环境引起的变化来实现的,例如当铁载体与铁原子螯合时,或者群体感应信号被特定的酶或吸附剂灭活时发生的变化。这些信息是由特定产生的分子在穿越环境时产生的化学和物理变化所捕获的,使细菌能够做出与环境相适应的反应。
Bacterial sensing circuits may be triggered by molecules originating from the environment (e.g., nutrients, chemoattractants). Bacteria also actively probe the environment for information, by releasing molecular probes to measure conditions beyond the cell surface -- telesensing. Perceiving the environment beyond is achieved by sensing environmentally induced changes in those probes, such as occurs when a siderophore chelates an iron atom, or a quorum sensing signal is inactivated by a specific enzyme or adsorbent. This information, captured by chemical and physical changes induced in specifically produced molecules transiting through the environment, enable bacteria to mount a contextually appropriate response.
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