Temperature Management Methods for Selective Brain Hypothermia in Variable Metabolism
Temperature Management Methods for Selective Brain Hypothermia in Variable Metabolism
复制标题
可变代谢中选择性脑低温的温度管理方法
DOI:
10.1002/tee.23384
复制
发表时间:
2021
影响因子:
1
通讯作者:
She Jinhua
中科院分区:
文献类型:
--
作者:
Honma Satoru;Wakamatsu Hidetoshi;She Jinhua
Brain hypothermia is widely operated to prevent peripheral healthy brain tissue from secondary damage, caused by increased brain temperature due to hypermetabolism around the damaged areas. Selective brain hypothermia is a new clinical technique of brain hypothermia for a brain disorder. Appropriate solution in a controlled temperature is directly infused into the artery to cool down a brain tissue through some catheters. While the brain temperature is controlled quickly, the body temperature has to be kept within a prescribed range by re‐warmed cerebrovascular blood return to the systemic circulation. As metabolic changes in the brain is variable due to the complex behavior of the disease state with the treatment effect. . In the present study two adaptive control methods as adaptive‐gain control and Fuzzy‐adaptive control are provided to carry out for precise temperature control for selective brain hypothermia. Several kinds of mathematical brain models with cerebrovascular damage are specially used to evaluate our temperature control methods. The effectiveness of the management of the brain temperature is demonstrated for four kinds control laws and five mathematical clinical brain models. © 2021 Institute of Electrical Engineers of Japan. Published by Wiley Periodicals LLC.
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