The association of PM(2.5) with full term low birth weight at different spatial scales.
The association of PM(2.5) with full term low birth weight at different spatial scales.
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DOI：
10.1016/j.envres.2014.05.034
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发表时间：
2014-10
影响因子：
8.3
通讯作者：
Wartenberg, Daniel
中科院分区：
文献类型：
--
作者：
Harris, Gerald;Thompson, W. Douglas;Fitzgerald, Edward;Wartenberg, Daniel
关键词：
人们有兴趣确定细颗粒物空气污染与各种健康结果之间的关系，包括足月低出生体重等出生结果。此前的研究得出了不同的结论。在这项研究中，我们考虑到这种影响是否会因位置和孕期而异。我们还比较了使用不同空间分辨率进行空气浓度估计时的结果。在所考虑的七个州中，新泽西州和纽约州的PM2.5水平最高(妊娠期平均暴露13μg/立方米)，低出生体重儿比率最高(分别为2.6%和2.8%)；相反，犹他州和明尼苏达州PM2.5水平最低(9μg/立方米)，低出生体重儿比率最低(分别为2.1%和1.9%)。在纽约，PM2.5暴露与低出生体重之间存在关联，在纽约，在整个妊娠期和所有三个月，在明尼苏达州，在整个妊娠期和前三个月，在新泽西州，在整个妊娠期和前三个月，PM2.5暴露与低出生体重有关。当我们跨州合并数据时，整个妊娠期的OR为1.030(95%CI：1.022-1.037)，在妊娠早期最高(OR 1.018；CI：1.013-1.022)，并在妊娠后期下降。当我们使用更精细的空间分辨率时，关联的强度往往会减弱，不再具有统计学意义。我们考虑了这些差异可能出现的原因，以及它们对评估PM2.5对出生结果的影响的意义。
There is interest in determining the relationship between fine particulate matter air pollution and various health outcomes, including birth outcomes such as term low birth weight. Previous studies have come to different conclusions. In this study we consider whether the effect may vary by location and gestational period. We also compare results when using different spatial resolutions for the air concentration estimates. Among the seven states considered, New Jersey and New York had the highest PM2.5 levels (average full gestation period exposures of 13 μg/m3) and the largest rate of low birth weight births (2.6 and 2.8%, respectively); conversely Utah and Minnesota had the lowest PM2.5 levels (9 μg/m3) and the lowest rates of low birth weight births (2.1 and1.9%, respectively). There is an association between PM2.5 exposure and low birth weight in New York for the full gestation period and all three trimesters, in Minnesota for the full gestation period and the first and third trimesters, and in New Jersey for the full gestation period and the first trimester. When we pooled the data across states, the OR for the full gestation period was 1.030 (95% CI: 1.022–1.037) and it was highest for the first trimester (OR 1.018; CI: 1.013–1.022) and decreasing during the later trimesters. When we used a finer spatial resolution, the strengths of the associations tended to diminish and were no longer statistically significant. We consider reasons why these differences may occur and their implications for evaluating the effects of PM2.5 on birth outcomes.
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影响因子：
10.4
作者：
Ebisu K;Bell ML
通讯作者：
Bell ML
影响因子：
8.3
作者：
Bravo MA;Fuentes M;Zhang Y;Burr MJ;Bell ML
通讯作者：
Bell ML
DOI：
10.1097/ede.0b013e3181f2f405
发表时间：
2010-11
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Bell ML;Belanger K;Ebisu K;Gent JF;Lee HJ;Koutrakis P;Leaderer BP
通讯作者：
Leaderer BP
影响因子：
8.3
作者：
Bell, Michelle L.;Belanger, Kathleen;Ebisu, Keita;Gent, Janneane F.;Leaderer, Brian P.
通讯作者：
Leaderer, Brian P.
影响因子：
10.4
作者：
Kannan S;Misra DP;Dvonch JT;Krishnakumar A
通讯作者：
Krishnakumar A