The modified bradykinesia rating scale for Parkinson's disease: reliability and comparison with kinematic measures.
The modified bradykinesia rating scale for Parkinson's disease: reliability and comparison with kinematic measures.
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DOI：
10.1002/mds.23740
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发表时间：
2011-08-15
影响因子：
8.6
通讯作者：
Espay, Alberto J.
中科院分区：
文献类型：
--
作者：
Heldman, Dustin A.;Giuffrida, Joseph P.;Chen, Robert;Payne, Megan;Mazzella, Filomena;Duker, Andrew P.;Sahay, Alok;Kim, Sang Jin;Revilla, Fredy J.;Espay, Alberto J.
关键词：
运动迟缓包括缓慢、运动幅度降低和节律障碍。统一帕金森病评定量表的缓激肽-sia相关项目要求临床医生将速度、振幅、疲劳、犹豫和停搏的异常浓缩为一个分数。本研究的目的是评价改良运动迟缓评定量表的可靠性，该量表分别评估速度、幅度和节律及其与运动传感器运动学测量的相关性。50名帕金森病患者在佩戴运动传感器时进行统一帕金森病评定量表指导的手指敲击、手抓握和旋前旋后。由4名临床医生对视频进行盲法独立评分。改良的运动迟缓评定量表和统一帕金森病评定量表具有相似的组间和组内信度。在分配统一帕金森病评定量表评分时，评分员对振幅的重视程度高于速度或节奏。改良运动迟缓评定量表的速度、幅度和节律评分与定量运动学变量高度相关。修改后的运动迟缓评定量表单独捕获运动迟缓组件，其评定者间和评定者内可靠性与统一帕金森病评定量表相似。运动传感器可以准确地量化速度、幅度和节奏，以帮助开发和评估帕金森病的新疗法。
Bradykinesia encompasses slowness, decreased movement amplitude, and dysrhythmia. Unified Parkinson’s Disease Rating Scale–based bradykine-sia-related items require that clinicians condense abnormalities in speed, amplitude, fatiguing, hesitations, and arrests into a single score. The objective of this study was to evaluate the reliability of a modified bradykinesia rating scale, which separately assesses speed, amplitude, and rhythm and its correlation with kinematic measures from motion sensors. Fifty patients with Parkinson’s disease performed Unified Parkinson’s Disease Rating Scale–directed finger tapping, hand grasping, and pronation–supination while wearing motion sensors. Videos were rated blindly and independently by 4 clinicians. The modified bradykinesia rating scale and Unified Parkinson’s Disease Rating Scale demonstrated similar inter- and intrarater reliability. Raters placed greater weight on amplitude than on speed or rhythm when assigning a Unified Parkinson’s Disease Rating Scale score. Modified bradykinesia rating scale scores for speed, amplitude, and rhythm correlated highly with quantitative kinematic variables. The modified bradykinesia rating scale separately captures bradykinesia components with interrater and intrarater reliability similar to that of the Unified Parkinson’s Disease Rating Scale. Kinematic sensors can accurately quantify speed, amplitude, and rhythm to aid in the development and evaluation of novel therapies in Parkinson’s disease.
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影响因子：
11
作者：
HENDERSON, L;KENNARD, C;PARK, DM
通讯作者：
PARK, DM
影响因子：
2.9
作者：
Kandori, A;Yokoe, M;Tsukada, K
通讯作者：
Tsukada, K
影响因子：
4.6
作者：
Salarian, Arash;Russmann, Heike;Aminian, Kamiar
通讯作者：
Aminian, Kamiar
影响因子：
8.6
作者：
Tavares, ALT;Jefferis, GSXE;Bronte-Stewart, HM
通讯作者：
Bronte-Stewart, HM
影响因子：
8.6
作者：
Giuffrida, Joseph P.;Riley, David E.;Heldman, Dustin A.
通讯作者：
Heldman, Dustin A.