Discrete place fields of hippocampal formation interneurons.
Discrete place fields of hippocampal formation interneurons.
复制标题
海马结构中间神经元的离散位置区域。
DOI:
10.1152/jn.01200.2006
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发表时间:
2007
影响因子:
2.5
通讯作者:
D. Nitz
中科院分区:
文献类型:
--
作者:
W. Wilent;D. Nitz;D. Nitz
The spike discharge of hippocampal excitatory principal cells, also called "place cells," is highly location specific, but the discharge of local inhibitory interneurons is thought to display relatively low spatial specificity. Whereas in other brain regions, such as sensory neocortex, the activity of interneurons is often exquisitely stimulus selective and directly determines the responses of neighboring excitatory neurons, the activity of hippocampal interneurons typically lacks the requisite specificity needed to shape the defined structure of principal cell fields. Here we show that hippocampal formation interneurons have "on" fields (abrupt increases in activity) and "off" fields (abrupt decreases in activity) that are associated with the same location-specific informational content, spatial resolution, and dependency on context as the "place fields" of CA1 principal cells. This establishes that interneurons have well-defined place fields, thus having important implications for understanding how the hippocampus represents spatial information.
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影响因子:
56.9
作者:
WILSON, MA;MCNAUGHTON, BL
通讯作者:
MCNAUGHTON, BL
影响因子:
2.5
作者:
Frank, LM;Brown, EN;Wilson, MA
通讯作者:
Wilson, MA
DOI:
10.1073/pnas.93.18.9921
发表时间:
1996-09-03
影响因子:
11.1
作者:
Buzsaki, G;Penttonen, M;Bragin, A
通讯作者:
Bragin, A
DOI:
--
发表时间:
1999
期刊:
Learning & memory (Cold Spring Harbor, N.Y.)
影响因子:
--
作者:
Nitz,DA;McNaughton,BL
通讯作者:
McNaughton,BL
影响因子:
56.9
作者:
BUZSAKI, G;HORVATH, Z;WISE, K
通讯作者:
WISE, K