Propensity for risky choices despite lower cue reactivity in adolescent rats.
Propensity for risky choices despite lower cue reactivity in adolescent rats.
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尽管青少年大鼠的提示反应性较低，但冒险选择的倾向。
DOI：
10.3389/fnbeh.2023.1297293
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发表时间：
2023
影响因子：
3
通讯作者：
Morrison, Sara E.
中科院分区：
文献类型：
--
作者：
Zeng, Sandford;McLaughlin, Elin F. B.;Ramesh, Aishwarya;Morrison, Sara E.
青春期是一个跨物种冒险的时期。与奖励相关的显著视听线索是赌博环境的一个共同特征，并且与增加的风险决策有关。我们以前已经表明，在成年雄性大鼠，标志跟踪-线索反应的行为措施-预测个人的倾向，次优的风险选择在啮齿动物赌博任务（rGT）与胜利配对的线索。然而，青少年比成年动物执行更少的符号跟踪，这表明他们在某些情况下比成年人更少的线索反应。因此，我们研究了青少年雄性大鼠在有胜利线索的rGT上的表现，并研究了其与符号追踪行为的关系。我们发现，青少年做出更多的风险选择和更少的最佳选择的rGT与成年人相比，rGT作为青少年赌博行为的模型的有效性的证据。我们还证实，青少年比成年人更少地进行符号跟踪，我们发现，与成年人不同，青少年的符号跟踪与他们在rGT中的冒险行为无关。这意味着青少年冒险比成年人更不可能受到与奖励相关的线索的驱使。最后，我们发现，在青少年时期接受rGT训练的成年人对冒险选择保持了类似于赌博的倾向，这表明早期接触赌博环境可能对冒险行为产生长期影响。
Adolescence is a time of heightened risk-taking across species. Salient audiovisual cues associated with rewards are a common feature of gambling environments and have been connected to increased risky decision-making. We have previously shown that, in adult male rats, sign tracking – a behavioral measure of cue reactivity – predicts an individual’s propensity for suboptimal risky choices in a rodent gambling task (rGT) with win-paired cues. However, adolescents perform less sign tracking than adult animals, suggesting that they are less cue-reactive than adults in some circumstances. Therefore, we investigated the performance of adolescent male rats on the rGT with win cues and examined its relationship with their sign-tracking behavior. We found that adolescents make more risky choices and fewer optimal choices on the rGT compared with adults, evidence of the validity of the rGT as a model of adolescent gambling behavior. We also confirmed that adolescents perform less sign tracking than adults, and we found that, unlike in adults, adolescents’ sign tracking was unrelated to their risk-taking in the rGT. This implies that adolescent risk-taking is less likely than that of adults to be driven by reward-related cues. Finally, we found that adults trained on the rGT as adolescents retained an adolescent-like propensity toward risky choices, suggesting that early exposure to a gambling environment may have a long-lasting impact on risk-taking behavior.
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影响因子：
4.7
作者：
Cho BR;Kwak MJ;Kim WY;Kim JH
通讯作者：
Kim JH
影响因子：
3.7
作者：
Clark, Jeremy J.;Nasrallah, Nicholas A.;Phillips, Paul E. M.
通讯作者：
Phillips, Paul E. M.
基于模型和无模型的Pavlovian奖励学习：重估，修订和启示。
DOI：
10.3758/s13415-014-0277-8
发表时间：
2014-06
期刊：
Cognitive, affective & behavioral neuroscience
影响因子：
--
作者：
Dayan P;Berridge KC
通讯作者：
Berridge KC
影响因子：
22.4
作者：
Defoe, Ivy N.;Dubas, Judith Semon;van Aken, Marcel A. G.
通讯作者：
van Aken, Marcel A. G.
影响因子：
5.3
作者：
Cherkasova, Mariya V.;Clark, Luke;Winstanley, Catharine A.
通讯作者：
Winstanley, Catharine A.