Neurobiology of gambling behaviors.

Neurobiology of gambling behaviors.
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DOI:
10.1016/j.conb.2013.03.004
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发表时间:
2013-08
影响因子:
5.7
通讯作者:
Potenza MN
Potenza MN
中科院分区:
医学2区
文献类型:
--
作者:
Potenza MN

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For many, gambling is a recreational activity that is performed periodically without ill effects, but for some, gambling may interfere with life functioning. A diagnostic entity, pathological gambling, is currently used to define a condition marked by excessive and problematic gambling. In this review, the current status of understanding of the neurobiologies of gambling and pathological gambling is described. Multiple neurotransmitter systems (norepinephrine, serotonin, dopamine, opioid and glutamate) and brain regions (ventral striatum, ventromedial prefrontal cortex, insula, among others) have been implicated in gambling and pathological gambling. Considerations for future directions in gambling research, with a view towards translating neurobiological advances into more effective prevention and treatment strategies, are discussed.
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