Epidemiology and transmission dynamics of West Nile virus disease.

Epidemiology and transmission dynamics of West Nile virus disease.
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DOI:
10.3201/eid1108.050289a
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发表时间:
2005-08
影响因子:
11.8
通讯作者:
Campbell GL
Campbell GL
中科院分区:
医学2区
文献类型:
--
作者:
Hayes EB;Komar N;Nasci RS;Montgomery SP;O'Leary DR;Campbell GL

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自1999年以来,美国有超过16,000例病例由库蚊传播。从1937年到1999年,西尼罗河病毒(WNV)作为非洲,亚洲和欧洲部分地区发热性疾病和散发性脑炎的原因,几乎没有引起医学关注。1999年在纽约市令人惊讶地发现西尼罗河病毒后,该病毒已急剧向西传播到整个美国,向南进入中美洲和加勒比海地区,向北进入加拿大,导致有史以来报道的最大规模的神经侵入性西尼罗河病毒疾病流行。从1999年到2004年,在美国报告了> 7,000例神经侵袭性西尼罗河病毒疾病病例。2002年,首次描述了通过输血和器官移植传播西尼罗河病毒,首次记录了宫内传播,并报告了可能通过母乳喂养传播。本文综述了西尼罗河病毒传播的流行病学和动力学的新信息,为进一步研究预防和控制西尼罗河病毒提供了新的平台。
Since 1999, >16,000 cases in the United Stateswere transmitted by Culex mosquitoes. From 1937 until 1999, West Nile virus (WNV) garnered scant medical attention as the cause of febrile illness and sporadic encephalitis in parts of Africa, Asia, and Europe. After the surprising detection of WNV in New York City in 1999, the virus has spread dramatically westward across the United States, southward into Central America and the Caribbean, and northward into Canada, resulting in the largest epidemics of neuroinvasive WNV disease ever reported. From 1999 to 2004, >7,000 neuroinvasive WNV disease cases were reported in the United States. In 2002, WNV transmission through blood transfusion and organ transplantation was described for the first time, intrauterine transmission was first documented, and possible transmission through breastfeeding was reported. This review highlights new information regarding the epidemiology and dynamics of WNV transmission, providing a new platform for further research into preventing and controlling WNV disease.
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