Dietary glycemic index, glycemic load, and lung cancer risk: A case-control study in Los Angeles County.
Dietary glycemic index, glycemic load, and lung cancer risk: A case-control study in Los Angeles County.
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DOI：
10.1016/j.canep.2020.101824
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发表时间：
2020-12
影响因子：
2.6
通讯作者：
Zhang ZF
中科院分区：
文献类型：
--
作者：
Chang CP;Meyers TJ;Fu A;Zhang MY;Tashkin DP;Rao JY;Cozen W;Mack TM;Hashibe M;Morgenstern H;Zhang ZF
虽然有一些证据表明血糖指数（GI）和血糖负荷（GL）与癌症风险之间存在正相关性，但与肺癌风险的关系在很大程度上尚未探索。我们评估了GI和GL与肺癌的关系。这些分析是使用1999年至2004年在洛杉矶县招募的基于人群的病例对照研究的数据进行的。饮食因素收集了593例肺癌病例和1026例对照使用修改的食物频率问卷。使用食物成分表估计GI和GL。使用调整潜在混杂因素的无条件logistic回归估计调整后的比值比（OR）和95%置信区间（CI）。饮食GI与肺癌呈正相关（上三分位数与下三分位数的OR = 1.62; 95% CI：1.17，2.25）。对于组织学亚型，GI与腺癌（上三分位数与下三分位数的OR = 1.82; 95% CI：1.22，2.70）和小细胞癌（上三分位数与下三分位数的OR = 2.68; 95% CI：1.25，5.74）之间存在正相关性。未观察到GL与肺癌之间存在明确关联。这些发现表明，高饮食GI与肺癌风险增加相关，并且观察到肺腺癌和小细胞肺癌的正相关性。在一个独立的数据集复制值得我们的结果进行更广泛的解释。
Although there is some evidence of positive associations between both the glycemic index (GI) and glycemic load (GL) with cancer risk, the relationships with lung cancer risk remain largely unexplored. We evaluated the associations between GI and GL with lung cancer. The analyses were performed using data from a population-based case-control study recruited between 1999 and 2004 in Los Angeles County. Dietary factors were collected from 593 incident lung cancer cases and 1026 controls using a modified food frequency questionnaire. GI and GL were estimated using a food composition table. Adjusted odds ratios (ORs) and 95% confidence intervals (CI) were estimated using unconditional logistic regression adjusting for potential confounders. Dietary GI was positively associated with lung cancer (OR for upper vs. lower tertile = 1.62; 95% CI: 1.17, 2.25). For histologic subtypes, positive associations were observed between GI and adenocarcinoma (OR for upper vs. lower tertile = 1.82; 95% CI: 1.22, 2.70) and small cell carcinoma (OR for upper vs. lower tertile = 2.68; 95% CI: 1.25, 5.74). No clear association between GL and lung cancer was observed. These findings suggest that high dietary GI was associated with increased lung cancer risk, and the positive associations were observed for both lung adenocarcinoma and small cell lung carcinoma. Replication in an independent dataset is merited for a broader interpretation of our results.
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影响因子：
--
作者：
Arcidiacono B;Iiritano S;Nocera A;Possidente K;Nevolo MT;Ventura V;Foti D;Chiefari E;Brunetti A
通讯作者：
Brunetti A
影响因子：
6.3
作者：
Leung, Gloria K. W.;Huggins, Catherine E.;Bonham, Maxine P.
通讯作者：
Bonham, Maxine P.
DOI：
10.3305/nh.2013.28.sup4.6802
发表时间：
2013-07-01
期刊：
Nutrición Hospitalaria
影响因子：
--
作者：
Aranceta Bartrina, Javier;Pérez Rodrigo, Carmen
通讯作者：
Pérez Rodrigo, Carmen
影响因子：
50.5
作者：
Hu, J.;La Vecchia, C.;Mery, L.
通讯作者：
Mery, L.
影响因子：
2.9
作者：
De Stefani, E;Deneo-Pellegrini, H;Carzoglio, JC
通讯作者：
Carzoglio, JC