Association between serum 25-hydroxyvitamin D and physical performance measures in middle-aged and old Japanese men and women: The Unzen study.
Association between serum 25-hydroxyvitamin D and physical performance measures in middle-aged and old Japanese men and women: The Unzen study.
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DOI：
10.1371/journal.pone.0261639
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Aoyagi K
中科院分区：
文献类型：
--
作者：
Uchiyama M;Mizukami S;Arima K;Nishimura T;Tomita Y;Abe Y;Tanaka N;Honda Y;Goto H;Hasegawa M;Sou Y;Tsujimoto R;Kanagae M;Osaki M;Aoyagi K
关于流行病学研究，维生素D在老年人肌肉骨骼功能（肌肉无力和身体表现）中的作用仍然存在争议。本研究的目的是调查25-羟基维生素D [25（OH）D]和身体性能之间的联系，在社区居住的中年和老年男性和女性的日本。研究对象是居住在社区的50岁以上的297名男性和415名女性。收集身高（m）和体重（kg）数据。测定血清25（OH）D、甲状旁腺激素、钙和白蛋白水平。血清25（OH）D分为缺乏组：< 20 ng/mL，不足组：20-30 ng/mL，充足组：> 30 ng/mL。通过握力、椅子站立时间和功能伸展来评估身体表现。收集当前吸烟、饮酒、定期锻炼、任何合并症（高血压、心脏病、糖尿病、肺病和中风）和疼痛（腰椎和膝关节）的信息。根据血清25（OH）D水平，分别在15.2%和56.9%的男性和52.0%和43.6%的女性中观察到维生素D缺乏和不足。在男性中，较高的血清25（OH）D水平与较好的握力（趋势p = 0.003），椅子站立时间（趋势p = 0.042）和功能范围（趋势p <0.001）相关。另一方面，这些参数与女性血清25（OH）D水平无关。较高水平的血清25（OH）D与男性较好的体能表现有关，但与女性无关。
Regarding epidemiological studies, the role of vitamin D in musculoskeletal functionality (muscle weakness and physical performance) among elderly people is still controversial. The purpose of the present study was to investigate the associations between 25-hydroxyvitamin D [25(OH)D] and physical performance among community-dwelling middle-aged and old Japanese men and women. The subjects were community-dwelling 297 men and 415 women aged 50 years and over. Data on height (m) and weight (kg) were collected. Serum 25(OH)D, parathyroid hormone, calcium, and albumin levels were measured. Serum 25(OH)D was classified into deficiency group: < 20 ng/mL, insufficiency group: 20–30 ng/mL, and sufficiency group: ≧ 30 ng/mL. Physical performance was assessed by grip strength, chair stand time, and functional reach. Information on current smoking, alcohol drinking, regular exercise, any comorbidities (hypertension, heart disease, diabetes mellitus, lung disease, and stroke), and pain (lumbar and knee) was collected. Vitamin D deficiency and insufficiency based on serum 25(OH)D levels were observed in 15.2% and 56.9% of men and 52.0% and 43.6% of women, respectively. In men, higher serum 25(OH)D levels were associated with better grip strength (p for trend = 0.003), chair stand time (p for trend = 0.042), and functional reach (p for trend <0.001). On the other hand, these parameters were not associated with serum 25(OH)D levels in women. A higher level of serum 25(OH)D was associated with better physical performance in men but not in women.
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影响因子：
4
作者：
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通讯作者：
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影响因子：
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影响因子：
5.4
作者：
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Ji HF
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影响因子：
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作者：
Halfon M;Phan O;Teta D
通讯作者：
Teta D
影响因子：
3.7
作者：
Kim TH;Hwang HJ;Kim SH
通讯作者：
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