A review of the "Omics" approach to biomarkers of oxidative stress in Oryza sativa.
A review of the "Omics" approach to biomarkers of oxidative stress in Oryza sativa.
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DOI：
10.3390/ijms14047515
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发表时间：
2013-04-08
影响因子：
5.6
通讯作者：
Lam SS
中科院分区：
文献类型：
--
作者：
Ma NL;Rahmat Z;Lam SS
造成作物生长缓慢和产量枯竭的生理和生态制约因素引起了农业行业的重大关切，因为它们可能构成未来粮食供应短缺的威胁。调控胁迫信号通路的关键特征始终与活性氧（reactive oxygen species， ROS）有关。植物细胞中ROS的积累会在基因组、蛋白质组和代谢组水平上留下生物标志物的痕迹，这可以通过最近的技术突破和生物信息学性能的提高来识别。本文综述了水稻氧化应激生物标志物鉴定的分子策略（包括转录组学、蛋白质组学和代谢组学）的最新进展，以及在水稻氧化应激生物标志物研究中出现的机遇和障碍。本文还讨论了结合生物信息学来验证来自不同基因组平台的生物标记物用于水稻育种计划的主要问题。氧化应激相关生物标志物鉴定技术的发展以及不同学科数据的整合为植物氧化反应途径的研究提供了新的思路。
Physiological and ecological constraints that cause the slow growth and depleted production of crops have raised a major concern in the agriculture industry as they represent a possible threat of short food supply in the future. The key feature that regulates the stress signaling pathway is always related to the reactive oxygen species (ROS). The accumulation of ROS in plant cells would leave traces of biomarkers at the genome, proteome, and metabolome levels, which could be identified with the recent technological breakthrough coupled with improved performance of bioinformatics. This review highlights the recent breakthrough in molecular strategies (comprising transcriptomics, proteomics, and metabolomics) in identifying oxidative stress biomarkers and the arising opportunities and obstacles observed in research on biomarkers in rice. The major issue in incorporating bioinformatics to validate the biomarkers from different omic platforms for the use of rice-breeding programs is also discussed. The development of powerful techniques for identification of oxidative stress-related biomarkers and the integration of data from different disciplines shed light on the oxidative response pathways in plants.
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