Inflammatory Bowel Diseases (IBD) and the Microbiome-Searching the Crime Scene for Clues.
Inflammatory Bowel Diseases (IBD) and the Microbiome-Searching the Crime Scene for Clues.
复制标题
DOI:
10.1053/j.gastro.2020.09.056
复制
发表时间:
2021-01
期刊:
影响因子:
29.4
通讯作者:
Chang EB
中科院分区:
文献类型:
--
作者:
Lee M;Chang EB
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial, immunological, and genetic factors. Alterations in the gut microbiota have been associated with development and progression of IBD, but it is not clear which populations of microbes are involved or how they might contribute to IBD. We review the genetic and environmental factors affecting the gut microbiota, the roles of gut microbes and their bioproducts in the development and clinical course of IBD, and strategies by which microbiome-based therapies can be used to prevent, manage, and eventually cure IBD. We discuss research findings that help bridge the gap between the basic sciences and clinical application.
登录
查看更多内容
影响因子:
64.8
作者:
Devkota, Suzanne;Wang, Yunwei;Musch, Mark W.;Leone, Vanessa;Fehlner-Peach, Hannah;Nadimpalli, Anuradha;Antonopoulos, Dionysios A.;Jabri, Bana;Chang, Eugene B.
通讯作者:
Chang, Eugene B.
DOI:
10.1126/science.1198469
发表时间:
2011-01-21
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Atarashi K;Tanoue T;Shima T;Imaoka A;Kuwahara T;Momose Y;Cheng G;Yamasaki S;Saito T;Ohba Y;Taniguchi T;Takeda K;Hori S;Ivanov II;Umesaki Y;Itoh K;Honda K
通讯作者:
Honda K
影响因子:
24.5
作者:
Ahmad, MS;Krishnan, S;Murthy, SN
通讯作者:
Murthy, SN
影响因子:
14.6
作者:
Azad, Meghan B.;Konya, Theodore;Kozyrskyj, Anita L.
通讯作者:
Kozyrskyj, Anita L.
影响因子:
2.2
作者:
Santos MPC;Gomes C;Torres J
通讯作者:
Torres J