Volumetric additive manufacturing of pristine silk-based (bio)inks.
Volumetric additive manufacturing of pristine silk-based (bio)inks.
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DOI：
10.1038/s41467-023-35807-7
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发表时间：
2023-01-13
影响因子：
16.6
通讯作者：
Zhang, Yu Shrike
中科院分区：
文献类型：
--
作者：
Xie, Maobin;Lian, Liming;Mu, Xuan;Luo, Zeyu;Garciamendez-Mijares, Carlos Ezio;Zhang, Zhenrui;Lopez, Arturo;Manriquez, Jennifer;Kuang, Xiao;Wu, Junqi;Sahoo, Jugal Kishore;Gonzalez, Federico Zertuche;Li, Gang;Tang, Guosheng;Maharjan, Sushila;Guo, Jie;Kaplan, David L.;Zhang, Yu Shrike
Volumetric additive manufacturing (VAM) enables fast photopolymerization of three-dimensional constructs by illuminating dynamically evolving light patterns in the entire build volume. However, the lack of bioinks suitable for VAM is a critical limitation. This study reports rapid volumetric (bio)printing of pristine, unmodified silk-based (silk sericin (SS) and silk fibroin (SF)) (bio)inks to form sophisticated shapes and architectures. Of interest, combined with post-fabrication processing, the (bio)printed SS constructs reveal properties including reversible as well as repeated shrinkage and expansion, or shape-memory; whereas the (bio)printed SF constructs exhibit tunable mechanical performances ranging from a few hundred Pa to hundreds of MPa. Both types of silk-based (bio)inks are cytocompatible. This work supplies expanded bioink libraries for VAM and provides a path forward for rapid volumetric manufacturing of silk constructs, towards broadened biomedical applications. Volumetric additive manufacturing of protein scaffolds has a wide range of possible biomedical applications. Here the authors report on the bioprinting of unmodified silk sericin and silk fibroin inks with shape-memory and tuneable mechanical properties and demonstrate the potential of the inks in different applications.
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影响因子：
16.6
作者：
Kim SH;Yeon YK;Lee JM;Chao JR;Lee YJ;Seo YB;Sultan MT;Lee OJ;Lee JS;Yoon SI;Hong IS;Khang G;Lee SJ;Yoo JJ;Park CH
通讯作者：
Park CH
DOI：
10.1002/adma.202104730
发表时间：
2021-12
期刊：
Advanced materials (Deerfield Beach, Fla.)
影响因子：
--
作者：
Ravanbakhsh H;Karamzadeh V;Bao G;Mongeau L;Juncker D;Zhang YS
通讯作者：
Zhang YS
影响因子：
16.6
作者：
Qin N;Qian ZG;Zhou C;Xia XX;Tao TH
通讯作者：
Tao TH
影响因子：
5
作者：
Mu X;Sahoo JK;Cebe P;Kaplan DL
通讯作者：
Kaplan DL
影响因子：
14
作者：
Qi, Chao;Liu, Jia;Wang, Lin
通讯作者：
Wang, Lin