Mosaic genome of endobacteria in arbuscular mycorrhizal fungi: Transkingdom gene transfer in an ancient mycoplasma-fungus association
Mosaic genome of endobacteria in arbuscular mycorrhizal fungi: Transkingdom gene transfer in an ancient mycoplasma-fungus association
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丛枝菌根真菌内细菌的花叶基因组:古代支原体-真菌协会中的跨界基因转移
DOI:
10.1073/pnas.1501540112
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发表时间:
2015
期刊:
影响因子:
--
通讯作者:
Arthur Schüßler
中科院分区:
文献类型:
--
作者:
Gloria Torres-Cortés;Stefano Ghignone;Paola Bonfante;Arthur Schüßler
For more than 450 million years, arbuscular mycorrhizal fungi (AMF) have formed intimate, mutualistic symbioses with the vast majority of land plants and are major drivers in almost all terrestrial ecosystems. The obligate plant-symbiotic AMF host additional symbionts, so-calledMollicutes-related endobacteria (MRE). To uncover putative functional roles of these widespread but yet enigmatic MRE, we sequenced the genome ofDhMRE living in the AMFDentiscutata heterogama. Multilocus phylogenetic analyses showed that MRE form a previously unidentified lineage sister to the hominis group ofMycoplasmaspecies.DhMRE possesses a strongly reduced metabolic capacity with 55% of the proteins having unknown function, which reflects unique adaptations to an intracellular lifestyle. We found evidence for transkingdom gene transfer between MRE and their AMF host. At least 27 annotatedDhMRE proteins show similarities to nuclear-encoded proteins of the AMFRhizophagus irregularis, which itself lacks MRE. Nuclear-encoded homologs could moreover be identified for another AMF,Gigaspora margarita, and surprisingly, also the non-AMFMortierella verticillata. Our data indicate a possible origin of the MRE-fungus association in ancestors of theGlomeromycotaandMucoromycotina. TheDhMRE genome encodes an arsenal of putative regulatory proteins with eukaryotic-like domains, some of them encoded in putative genomic islands. MRE are highly interesting candidates to study the evolution and interactions between an ancient, obligate endosymbiotic prokaryote with its obligate plant-symbiotic fungal host. Our data moreover may be used for further targeted searches for ancient effector-like proteins that may be key components in the regulation of the arbuscular mycorrhiza symbiosis.
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影响因子:
15.9
作者:
Al-Quadan, Tasneem;Price, Christopher T.;Abu Kwaik, Yousef
通讯作者:
Abu Kwaik, Yousef
影响因子:
9.4
作者:
Desiro, Alessandro;Faccio, Antonella;Bonfante, Paola
通讯作者:
Bonfante, Paola
影响因子:
11.6
作者:
Reuber, TL;Ausubel, FM
通讯作者:
Ausubel, FM
影响因子:
3.5
作者:
Carvalho, FM;Fonseca, MM;Agnez-Lima, LF
通讯作者:
Agnez-Lima, LF
DOI:
--
发表时间:
1970
期刊:
Archiv für Mikrobiologie
影响因子:
--
作者:
B. Mosse
通讯作者:
B. Mosse