Thalamic integration of social stimuli regulating parental behavior and the oxytocin system.
Thalamic integration of social stimuli regulating parental behavior and the oxytocin system.
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DOI：
10.1016/j.yfrne.2018.05.002
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发表时间：
2018-10
影响因子：
7.4
通讯作者：
Young LJ
中科院分区：
文献类型：
--
作者：
Dobolyi A;Cservenák M;Young LJ
最近确定了哺乳强烈激活的视前区的母体神经回路的至关重要的组成部分。反过来，哺乳也有助于荷尔蒙适应母性，包括催产素的释放和随后的乳汁排出。其他生殖或社会刺激也可以触发催产素的集中释放，影响父母或社会行为。然而，将吮吸和其他躯体感觉刺激传递到视前区和催产素神经元的神经元通路的特征很差。最近，哺乳中继中心的确定和特点是在后板内复合体的丘脑（PIL）。其含有tuberoinfundibular肽39的神经元投射到下丘脑的视前区和催产素神经元。本综述认为，PIL是一个主要的中继核团传递躯体感觉信息，支持母亲的行为和催产素的释放，并可能参与更广泛的社会线索诱发催产素的释放，太。
Critically important components of the maternal neural circuit in the preoptic area robustly activated by suckling were recently identified. In turn, suckling also contributes to hormonal adaptations to motherhood, which includes oxytocin release and consequent milk ejection. Other reproductive or social stimuli can also trigger the release of oxytocin centrally, influencing parental or social behaviors. However, the neuronal pathways that transfer suckling and other somatosensory stimuli to the preoptic area and oxytocin neurons have been poorly characterized. Recently, a relay center of suckling was determined and characterized in the posterior intralaminar complex of the thalamus (PIL). Its neurons containing tuberoinfundibular peptide 39 project to both the preoptic area and oxytocin neurons in the hypothalamus. The present review argues that the PIL is a major relay nucleus conveying somatosensory information supporting maternal behavior and oxytocin release in mothers, and may be involved more generally in social cue evoked oxytocin release, too.
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影响因子：
3.1
作者：
Cservenák M;Kis V;Keller D;Dimén D;Menyhárt L;Oláh S;Szabó ÉR;Barna J;Renner É;Usdin TB;Dobolyi A
通讯作者：
Dobolyi A
影响因子：
5.3
作者：
Bale, TL;Davis, AM;McCarthy, MM
通讯作者：
McCarthy, MM
DOI：
10.1152/ajpendo.1998.274.3.e453
发表时间：
1998-03-01
影响因子：
5.1
作者：
Bealer, SL;Crowley, WR
通讯作者：
Crowley, WR
影响因子：
4.1
作者：
Bridges, RS;Robertson, MC;Mann, PE
通讯作者：
Mann, PE
DOI：
10.1073/pnas.87.20.8003
发表时间：
1990-10-01
影响因子：
11.1
作者：
BRIDGES, RS;NUMAN, M;LUPINI, CE
通讯作者：
LUPINI, CE