Role of the anterior insula in task-level control and focal attention.
Role of the anterior insula in task-level control and focal attention.
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DOI:
10.1007/s00429-010-0260-2
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发表时间:
2010-06
影响因子:
3.1
通讯作者:
Petersen, Steven E.
中科院分区:
文献类型:
--
作者:
Nelson, Steven M.;Dosenbach, Nico U. F.;Cohen, Alexander L.;Wheeler, Mark E.;Schlaggar, Bradley L.;Petersen, Steven E.
In humans, the anterior insula (aI) has been the topic of considerable research and ascribed a vast number of functional properties by way of neuroimaging and lesion studies. Here, we argue that the aI, at least in part, plays a role in domain-general attentional control and highlight studies (Dosenbach et al.; Dosenbach et al.) supporting this view. Additionally, we discuss a study (Ploran et al.) that implicates aI in processes related to the capture of focal attention. Task-level control and focal attention may or may not reflect information processing supported by a single functional area (within the aI). Therefore, we apply a novel technique (Cohen et al.) that utilizes resting state functional connectivity MRI (rs-fcMRI) to determine whether separable regions exist within the aI. rs-fcMRI mapping suggests that the ventral portion of the aI is distinguishable from more dorsal/anterior regions, which are themselves distinct from more posterior parts of the aI. When these regions are applied to functional MRI (fMRI) data, the ventral and dorsal/anterior regions support processes potentially related to both task-level control and focal attention, whereas the more posterior aI regions did not. These findings suggest that there exists some functional heterogeneity within aI that may subserve related but distinct types of higher-order cognitive processing. The online version of this article (doi:10.1007/s00429-010-0260-2) contains supplementary material, which is available to authorized users.
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DOI:
10.1073/pnas.0504136102
发表时间:
2005-07-05
影响因子:
11.1
作者:
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通讯作者:
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作者:
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DOI:
10.1523/jneurosci.3363-08.2009
发表时间:
2009-02-11
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
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通讯作者:
Critchley HD