Perinatal environmental exposures affect mammary development, function, and cancer risk in adulthood.
Perinatal environmental exposures affect mammary development, function, and cancer risk in adulthood.
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DOI:
10.1146/annurev-pharmtox-010611-134659
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发表时间:
2012
影响因子:
12.5
通讯作者:
Newbold RR
中科院分区:
文献类型:
--
作者:
Fenton SE;Reed C;Newbold RR
Puberty is an important transition that enables reproduction of mammalian species. Precocious puberty, specifically early thelarche (the appearance of breast “buds”), in girls of multiple ethnic backgrounds is a major health problem in the United States and other countries. The cause for a continued decrease in the age of breast development in girls is unknown, but environmental factors likely play a major role. Laboratory and epidemiological studies have identified several individual environmental factors that affect breast development, but further progress is needed. Current research needs include increased attention to and recording of prenatal and neonatal environmental exposures, testing of marketed chemicals for effects on the mammary gland, and understanding of the mammary gland–specific mechanisms that are altered by chemicals. Such research is required to halt the increasing trend toward puberty at earlier ages.
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影响因子:
8
作者:
Biro FM;Galvez MP;Greenspan LC;Succop PA;Vangeepuram N;Pinney SM;Teitelbaum S;Windham GC;Kushi LH;Wolff MS
通讯作者:
Wolff MS
影响因子:
11.8
作者:
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Marcus M
影响因子:
3.6
作者:
BOYLAN, ES
通讯作者:
BOYLAN, ES
DOI:
10.1080/15287390490483818
发表时间:
2004-09-24
影响因子:
2.6
作者:
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通讯作者:
Tsang, BK
影响因子:
10.4
作者:
Birnbaum LS;Fenton SE
通讯作者:
Fenton SE