Rethinking the role of taste processing in insular cortex and forebrain circuits.
Rethinking the role of taste processing in insular cortex and forebrain circuits.
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DOI:
10.1016/j.cophys.2020.12.009
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发表时间:
2021-04
影响因子:
2.5
通讯作者:
Fletcher M
中科院分区:
文献类型:
--
作者:
Boughter JD Jr;Fletcher M
Over the years, many approaches towards studying the taste-responsive area of insular cortex have focused on how basic taste information is represented, and how lesions or silencing of this area impact taste-focused behaviors. Here, we review and highlight recent studies that imply that insular cortex does not contain a “primary” taste cortex in the traditional sense. Rather, taste is employed in concert with other internal and external sensory modalities by highly interconnected regions of insular cortex to guide ingestive decision-making, especially in context of estimating risk and reward. In rodent models, this may best be seen in context of foraging behaviors, which require flexibility and are dependent on learning and memory processes.
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