Associations between indoor relative humidity and global COVID-19 outcomes.
Associations between indoor relative humidity and global COVID-19 outcomes.
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室内相对湿度与全球互联19结果之间的关联。
DOI：
10.1098/rsif.2021.0865
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发表时间：
2022-11
期刊：
影响因子：
--
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中科院分区：
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--
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在全球范围内，新冠肺炎的传播范围和严重程度明显参差不齐。季节性被认为是造成地区差异的原因，但天气和新冠肺炎之间的关系仍不清楚，人们关注的焦点一直是户外条件。由于人类大部分时间在室内度过，而且大多数传播发生在室内，我们在这里研究的是室内气候--特别是室内相对湿度(RH)--可能是更相关的疫情调节因素的假设。为了研究这种联系，我们结合了基于人口的新冠肺炎统计数据和来自121个国家的气象测量数据。我们严格处理流行病学数据以减少偏差，然后开发并实验验证基于室外天气数据和标准室内舒适度条件估计室内条件的计算工作流程。我们的综合分析表明，区域性暴发和室内相对湿度之间存在强大而系统的关系。特别是，我们发现中度相对湿度(40-60%)与较好的新冠肺炎暴发结果密切相关(而相对湿度为40%或60%)。总之，这些结果表明，室内条件，特别是室内相对湿度，调节了新冠肺炎疫情的传播和严重程度。
Globally, the spread and severity of COVID-19 have been distinctly non-uniform. Seasonality was suggested as a contributor to regional variability, but the relationship between weather and COVID-19 remains unclear and the focus of attention has been on outdoor conditions. Because humans spend most of their time indoors and because most transmission occurs indoors, we here, instead, investigate the hypothesis that indoor climate—particularly indoor relative humidity (RH)—may be the more relevant modulator of outbreaks. To study this association, we combined population-based COVID-19 statistics and meteorological measurements from 121 countries. We rigorously processed epidemiological data to reduce bias, then developed and experimentally validated a computational workflow to estimate indoor conditions based on outdoor weather data and standard indoor comfort conditions. Our comprehensive analysis shows robust and systematic relationships between regional outbreaks and indoor RH. In particular, we found intermediate RH (40–60%) to be robustly associated with better COVID-19 outbreak outcomes (versus RH < 40% or >60%). Together, these results suggest that indoor conditions, particularly indoor RH, modulate the spread and severity of COVID-19 outbreaks.
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