Gradient-index lens rod based probe for office-based optical coherence tomography of the human larynx.

Gradient-index lens rod based probe for office-based optical coherence tomography of the human larynx.
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DOI:
10.1117/1.3076198
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发表时间:
2009-01
影响因子:
3.5
通讯作者:
Chen Z
Chen Z
中科院分区:
医学3区
文献类型:
--
作者:
Guo S;Yu L;Sepehr A;Perez J;Su J;Ridgway JM;Vokes D;Wong BJ;Chen Z

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光学相干断层扫描(OCT)是一种不断发展的非侵入性成像模式,已被用于在外科内窥镜检查期间对人体喉部进行成像。提出了一种基于长梯度折射率透镜的探头的设计,该探头能够在典型的基于办公室的喉镜检查期间通过使用谱域OCT来捕获人类喉部的图像。提出了一种基于光镇流器的4f光中继系统,实现了在恒定光延迟下的可变工作距离。人体喉部的体内OCT成像被证明。OCT是一种很有前途的早期喉癌诊断方法。
Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient-index lens-based probe capable of capturing images of the human larynx by use of spectral domain OCT during a typical office-based laryngoscopy examination is presented. An optical-ballast-based 4f optical relay system is proposed to realize variable working distance with a constant optical delay. In-vivo OCT imaging of the human larynx is demonstrated. Office-based OCT is a promising imaging modality for early laryngeal cancer diagnosis.
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