A face a mother could love: depression-related maternal neural responses to infant emotion faces.
A face a mother could love: depression-related maternal neural responses to infant emotion faces.
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DOI：
10.1080/17470919.2012.762039
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发表时间：
2013
影响因子：
2
通讯作者：
Ablow JC
中科院分区：
文献类型：
--
作者：
Laurent HK;Ablow JC
抑郁的母亲对婴儿的情绪表现出消极的偏见反应，这可能是由于对婴儿线索的错误处理。这项研究是第一个研究抑郁相关的差异，母亲的神经反应，自己的婴儿的情绪面孔，考虑到围产期抑郁症的历史和目前的抑郁症状的影响。初产母亲（n = 22），其中一半的历史，重度抑郁发作（一次发作发生在怀孕期间和/或产后），暴露于自己的图像和不熟悉的婴儿的喜悦和痛苦的面孔在功能性神经成像。组差异（抑郁症与无抑郁症）和当前抑郁症状的持续影响进行了测试，与自己的婴儿情绪面孔的神经反应。与没有精神病诊断的母亲相比，那些患有抑郁症的母亲在背侧前扣带皮层对自己婴儿的痛苦表情反应迟钝。具有较高水平的当前情绪学的母亲在眶额皮层和额叶皮层对自己婴儿的喜悦表情表现出较低的反应。目前的情绪学还预测，左侧前额叶和纹状体/纹状体区域对自己的婴儿快乐-痛苦的反应较低。这些自我调节和动机反应回路的缺陷可能有助于解释抑郁母亲的育儿困难。
Depressed mothers show negatively biased responses to their infants’ emotional bids, perhaps due to faulty processing of infant cues. This study is the first to examine depression-related differences in mothers’ neural response to their own infant’s emotion faces, considering both effects of perinatal depression history and current depressive symptoms. Primiparous mothers (n = 22), half of whom had a history of major depressive episodes (with one episode occurring during pregnancy and/or postpartum), were exposed to images of their own and unfamiliar infants’ joy and distress faces during functional neuroimaging. Group differences (depression vs. no-depression) and continuous effects of current depressive symptoms were tested in relation to neural response to own infant emotion faces. Compared to mothers with no psychiatric diagnoses, those with depression showed blunted responses to their own infant’s distress faces in the dorsal anterior cingulate cortex. Mothers with higher levels of current symptomatology showed reduced responses to their own infant’s joy faces in the orbital-frontal cortex and insula. Current symptomatology also predicted lower responses to own infant joy–distress in left-sided prefrontal and insula/striatal regions. These deficits in self-regulatory and motivational response circuits may help explain parenting difficulties in depressed mothers.
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影响因子：
2.3
作者：
Lacerda, ALT;Nicoletti, MA;Soares, JC
通讯作者：
Soares, JC
影响因子：
2.3
作者：
Kerestes, Rebecca;Bhagwagar, Zubin;Nathan, Pradeep J.;Meda, Shashwath A.;Ladouceur, Cecile D.;Maloney, Kathleen;Matuskey, David;Ruf, Barbara;Saricicek, Aybala;Wang, Fei;Pearlson, Godfrey D.;Phillips, Mary L.;Blumberg, Hilary P.
通讯作者：
Blumberg, Hilary P.
影响因子：
4.2
作者：
Laurent, Heidemarie K.;Ablow, Jennifer C.
通讯作者：
Ablow, Jennifer C.
影响因子：
5.3
作者：
Harsay, Helga A.;Cohen, Michael X.;Ridderinkhof, K. Richard
通讯作者：
Ridderinkhof, K. Richard
影响因子：
17.7
作者：
Liotti, M;Mayberg, HS;Jerabek, P
通讯作者：
Jerabek, P