Injectable synthetic extracellular matrices for tissue engineering and repair.
Injectable synthetic extracellular matrices for tissue engineering and repair.
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用于组织工程和修复的可注射合成细胞外基质。
DOI:
10.1007/978-0-387-34133-0_9
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发表时间:
2006
影响因子:
--
通讯作者:
Smith,MarshallE
中科院分区:
文献类型:
--
作者:
Prestwich,GlennD;Shu,XiaoZheng;Liu,Yanchun;Cai,Shenshen;Walsh,JenniferF;Hughes,CaseyW;Ahmad,Shama;Kirker,KellyR;Yu,Bolan;Orlandi,RichardR;Park,AlbertH;Thibeault,SusanL;Duflo,Suzy;Smith,MarshallE
The development of novel biointeractive hydrogels for tissue engineering1–3, tissue repair, and release of drugs4 and growth factors5 has attracted considerable attention over the past decade. Our attention has focused on hydrogels based on the extracellular matrix (ECM), a heterogeneous collection of covalent and noncovalent molecular interactions comprised primary of proteins and glycosaminoglycans (GAGs)6. In the ECM, covalent interactions connect chondroitin sulfate (CS), heparan sulfate (HS) and other sulfated GAGs to core proteins forming proteoglycans (PGs). Noncovalent interactions include binding of link modules of PGs to hyaluronan (HA), electrostatic associations with ions, hydration of the polysaccharide chains, and triple helix formation to generate collagen fibrils.
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影响因子:
10.8
作者:
Anseth, KS;Metters, AT;Bowman, CN
通讯作者:
Bowman, CN
影响因子:
14
作者:
Peattie, RA;Rieke, ER;Prestwich, GD
通讯作者:
Prestwich, GD
影响因子:
6.2
作者:
Shu, XZ;Liu, YC;Prestwich, GD
通讯作者:
Prestwich, GD
影响因子:
14
作者:
Kirker, KR;Luo, Y;Prestwich, GD
通讯作者:
Prestwich, GD
影响因子:
6.7
作者:
Liu, YC;Li, H;Prestwich, GD
通讯作者:
Prestwich, GD