Prolinks: a database of protein functional linkages derived from coevolution.
Prolinks: a database of protein functional linkages derived from coevolution.
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DOI:
10.1186/gb-2004-5-5-r35
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发表时间:
2004
期刊:
影响因子:
12.3
通讯作者:
Eisenberg D
中科院分区:
文献类型:
--
作者:
Bowers PM;Pellegrini M;Thompson MJ;Fierro J;Yeates TO;Eisenberg D
Four methods that infer protein function and linkages have been combined in a single database, Prolinks, which spans 83 organisms and includes 10 million high-confidence links. The advent of whole-genome sequencing has led to methods that infer protein function and linkages. We have combined four such algorithms (phylogenetic profile, Rosetta Stone, gene neighbor and gene cluster) in a single database - Prolinks - that spans 83 organisms and includes 10 million high-confidence links. The Proteome Navigator tool allows users to browse predicted linkage networks interactively, providing accompanying annotation from public databases. The Prolinks database and the Proteome Navigator tool are available for use online at .
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影响因子:
12.3
作者:
Strong, Michael;Mallick, Parag;Pellegrini, Matteo;Thompson, Michael J;Eisenberg, David
通讯作者:
Eisenberg, David
影响因子:
13.8
作者:
Dandekar, T;Snel, B;Bork, P
通讯作者:
Bork, P
影响因子:
64.8
作者:
Marcotte, EM;Pellegrini, M;Eisenberg, D
通讯作者:
Eisenberg, D
影响因子:
4
作者:
Pellegrini, M;Thompson, M;Bowers, P
通讯作者:
Bowers, P
影响因子:
14.9
作者:
Ermolaeva, MD;White, O;Salzberg, SL
通讯作者:
Salzberg, SL