Unique environmental effects on physical activity participation: a twin study.
Unique environmental effects on physical activity participation: a twin study.
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对体育活动参与的独特环境影响：一项双胞胎研究。
DOI：
10.1371/journal.pone.0002019
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发表时间：
2008-04-16
期刊：
影响因子：
3.7
通讯作者：
Buchwald, Dedra
中科院分区：
文献类型：
--
作者：
Duncan, Glen E.;Goldberg, Jack;Noonan, Carolyn;Moudon, Anne Vernez;Hurvitz, Philip;Buchwald, Dedra
定期体育活动对健康的好处是众所周知的。然而，遗传和环境因素对身体活动参与的相对贡献仍然存在争议。使用每周总活动时间为60分钟的临界点，来自GenomEUtwin项目的数据显示，来自7个国家的37，051对双胞胎对身体活动参与的遗传影响一致。我们假设，使用CDC/ACSM推荐的每周150分钟中等强度活动的最低阈值，体力活动参与的遗传性会减弱。数据来自社区为基础的华盛顿大学双胞胎登记处的1,389对双胞胎。双胞胎相似的身体活动参与使用两个切割点进行了分析，使用四项相关和结构方程模型在所有同性对。使用60分钟临界点时，单合子对（rMZ = 0.43，95% CI = 0.33-0.54）的相关性高于双合子对（rDZ = 0.30，95% CI =0.12-0.47）。 然而，使用150分钟标准品时，差异减弱（rMZ = 0.30，95% CI = 0.20-0.40; rDZ = 0.25，95% CI = 0.07-0.42）。 以下限为界点，双生子相似性的最佳拟合模型仅包括加性遗传和独特环境，遗传率为45%。相比之下，使用更高的阈值，最佳拟合模型包括共同和独特的环境，独特的环境贡献了72%的方差。独特的环境因素对身体活动参与的影响最大，建议的健康益处水平。
The health benefits of regular physical activity are well established. However, the relative contribution of heritable and environmental factors to physical activity participation remains controversial. Using a cut-point of 60 minutes of total activity per week, data from the GenomEUtwin project revealed consistent genetic influence on physical activity participation in 37,051 twin pairs from seven countries. We hypothesized that the heritability of physical activity participation would be attenuated using the CDC/ACSM recommended minimum threshold of 150 minutes of moderate intensity activity per week. Data were obtained from 1,389 twin pairs from the community-based University of Washington Twin Registry. Twin similarity in physical activity participation using both cut-points was analyzed using tetrachoric correlations and structural equation modeling in all same-sex pairs. Correlations were higher in monozygotic (rMZ = 0.43, 95% CI = 0.33–0.54) than dizygotic pairs (rDZ = 0.30, 95% CI = 0.12–0.47) using the 60 minute cut-point. However, differences were attenuated using the 150 minute standard (rMZ = 0.30, 95% CI = 0.20–0.40; rDZ = 0.25, 95% CI = 0.07–0.42). Using the lower cut-point, the best fitting model of twin resemblance only included additive genetics and unique environment, with a heritability of 45%. In contrast, using the higher threshold, the best fitting model included the common and unique environment, with the unique environment contributing 72% of the variance. Unique environment factors provide the strongest influence on physical activity participation at levels recommended for health benefits.
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影响因子：
120.7
作者：
PATE, RR;PRATT, M;WILMORE, JH
通讯作者：
WILMORE, JH
影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
DOI：
10.1249/01.mss.0000228941.17034.c1
发表时间：
2006-08-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Carlsson, Sofia;Andersson, Tomas;Ahlbom, Anders
通讯作者：
Ahlbom, Anders
影响因子：
2.6
作者：
Eriksson, M;Rasmussen, F;Tynelius, P
通讯作者：
Tynelius, P
DOI：
10.1097/00005768-200207000-00014
发表时间：
2002-07-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Simonen, RL;Pérusse, L;Bouchard, C
通讯作者：
Bouchard, C