Virulence factors for hemolytic uremic syndrome, Denmark.
Virulence factors for hemolytic uremic syndrome, Denmark.
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DOI:
10.3201/eid1005.030576
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发表时间:
2004-05
影响因子:
11.8
通讯作者:
Mølbak K
中科院分区:
文献类型:
--
作者:
Ethelberg S;Olsen KE;Scheutz F;Jensen C;Schiellerup P;Enberg J;Petersen AM;Olesen B;Gerner-Smidt P;Mølbak K
We present an analysis of strain and patient factors associated with the development of bloody diarrhea and hemolytic uremic syndrome (HUS) among Shiga toxin-producing Escherichia coli (STEC) patients registered in Denmark in a 6-year period. Of 343 STEC patients, bloody diarrhea developed in 36.4% and HUS in 6.1%. In a multivariate logistic regression model, risk factors for bloody diarrhea were the eae and stx2 genes, O groups O157 and O103, and increasing age. Risk factors for HUS were presence of the stx2 (odds ratio [OR] 18.9) and eae (OR undefined) genes, being a child, and having bloody diarrhea. O group O157, although associated with HUS in a univariate analysis (OR 4.0), was not associated in the multivariate analysis (OR 1.1). This finding indicates that, rather than O group, the combined presence of the eae and stx2 genes is an important predictor of HUS.
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影响因子:
9.4
作者:
Blom, M;Meyer, A;Espersen, F
通讯作者:
Espersen, F
影响因子:
9.4
作者:
Boerlin, P;McEwen, SA;Gyles, CL
通讯作者:
Gyles, CL
DOI:
10.1007/s10096-003-1025-0
发表时间:
2003-12-01
影响因子:
4.5
作者:
Werber, D;Fruth, A;Tsch채pe, H
通讯作者:
Tsch채pe, H
影响因子:
6.4
作者:
Friedrich, AW;Bielaszewska, M;Karch, H
通讯作者:
Karch, H
影响因子:
11.8
作者:
Beutin, L;Zimmermann, S;Gleier, K
通讯作者:
Gleier, K