New methods in diffusion-weighted and diffusion tensor imaging.

New methods in diffusion-weighted and diffusion tensor imaging.
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DOI:
10.1016/j.mric.2009.01.011
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发表时间:
2009-05
影响因子:
1.6
通讯作者:
Skare, Stefan T.
Skare, Stefan T.
中科院分区:
医学4区
文献类型:
--
作者:
Bammer, Roland;Holdsworth, Samantha J.;Veldhuis, Wouter B.;Skare, Stefan T.

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在扩散加权成像(DWI)方面,无数的个人研究人员已经取得了长足的进步,将DWI从一种实验工具(仅限于少数具有专门仪器的机构)推向了常规诊断成像的强大工具。尽管目前取得了成功,但DWI领域仍在不断发展,并在几个方面取得了进展,等待供应商和临床用户采用下一代DWI。这些发展主要包括提高对患者和生理运动的鲁棒性,增加空间分辨率,新的生物物理和组织模型,以及DWI的新的临床应用。本文旨在简要概述其中的一些新发展,并描述与DWI相关的一些主要挑战。尝试理解这些挑战不仅对精通技术的MRI用户有帮助,而且对对这些技术的潜在优势和弱点感兴趣的放射科医生也有帮助,“扩散管道”是什么,以及如何解释DWI扫描上的伪影。
Considerable strides have been made by countless individual researchers in diffusion-weighted imaging (DWI) to push DWI from an experimental tool – limited to a few institutions with specialized instrumentation – to a powerful tool used routinely for diagnostic imaging. Despite its current success, the field of DWI constantly evolves and progress has been made on several fronts, awaiting adoption by vendors and clinical users to bring in the next generation of DWI. These developments are primarily comprised of improved robustness against patient and physiologic motion, increased spatial resolution, new biophysical and tissue models, and new clinical applications for DWI. This article aims to provide a succinct overview of some of these new developments and a description of some of the major challenges associated with DWI. Trying to understand some of these challenges is helpful not only to the technically savvy MRI user, but also to radiologists who are interested in the potential strengths and weaknesses of these techniques, what is in the “diffusion pipeline”, and in how to interpret artifacts on DWI scans.
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