Scleral Thickness in Steroid-Induced Central Serous Chorioretinopathy.
Scleral Thickness in Steroid-Induced Central Serous Chorioretinopathy.
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DOI：
10.1016/j.xops.2022.100124
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发表时间：
2022-06
影响因子：
--
通讯作者：
Koizumi, Hideki
中科院分区：
文献类型：
--
作者：
Sawaguchi, Shota;Terao, Nobuhiro;Imanaga, Naoya;Wakugawa, Sorako;Tamashiro, Tamaki;Yamauchi, Yukihide;Koizumi, Hideki
应用前段oct技术评价和比较特发性中枢性浆液性绒毛膜视网膜病变（iCSC）和类固醇诱导的中枢性浆液性绒毛膜视网膜病变（sCSC）患者的巩膜厚度。110例中枢性浆液性脉络膜视网膜病变110只眼。我们将患者分为iCSC组和sCSC组，并比较年龄、性别、球形当量、轴向长度、中央凹下脉络膜厚度（SCT）和巩膜厚度。我们测量了巩膜厚度在巩膜骨刺后6毫米，在4个方向。sCSC眼巩膜厚度。我们在iCSC组和sCSC组分别入组96只和14只眼。sCSC组的女性比例高于iCSC组（分别为42.9%和13.5%,P = 0.020）。我们观察到两组之间在年龄、球当量、轴向长度或SCT方面没有差异。单因素分析显示，与iCSC组相比，sCSC组在上点（423.4 μm vs. 346.6 μm, P < 0.001）、颞点（440.1 μm vs. 399.4 μm, P = 0.020）、下点（450.1 μm vs. 395.3 μm, P = 0.001）和鼻点（436.6 μm vs. 391.9 μm, P = 0.002）的巩膜明显更薄。多因素分析显示，女性（优势比为4.322,95%可信区间为1.025 ~ 18.224,P = 0.046）和巩膜平均厚度（优势比为0.972,95%可信区间为0.955 ~ 0.990,P = 0.002）与sCSC显著相关。sCSC组眼巩膜厚度明显薄于iCSC组。这表明巩膜在sCSC发病机制中的作用小于iCSC。
To evaluate and compare the scleral thickness of patients with idiopathic central serous chorioretinopathy (iCSC) and steroid-induced central serous chorioretinopathy (sCSC) using anterior-segment OCT. Retrospective, comparative study. One hundred ten eyes of 110 patients with central serous chorioretinopathy. We classified the patients into iCSC and sCSC groups and compared age, sex, spherical equivalent, axial length, subfoveal choroidal thickness (SCT), and scleral thickness. We measured scleral thickness 6 mm posterior to the scleral spur in 4 directions. Scleral thickness in sCSC eyes. We enrolled 96 and 14 eyes in the iCSC and sCSC groups, respectively. The sCSC group included a greater proportion of women than the iCSC group (42.9% and 13.5%, respectively; P = 0.020). We observed no between-group differences in age, spherical equivalent, axial length, or SCT. Univariate analysis revealed that the sCSC group had a significantly thinner sclera at the superior (423.4 μm vs. 346.6 μm; P < 0.001), temporal (440.1 μm vs. 399.4 μm; P = 0.020), inferior (450.1 μm vs. 395.3 μm; P = 0.001), and nasal (436.6 μm vs. 391.9 μm; P = 0.002) points than the iCSC group. Multivariate analyses revealed that female sex (odds ratio, 4.322; 95% confidence interval, 1.025–18.224; P = 0.046) and mean scleral thickness (odds ratio, 0.972; 95% confidence interval, 0.955–0.990; P = 0.002) were significantly associated with sCSC. The scleral thickness of eyes in the sCSC group was significantly thinner than that in the iCSC group. This suggests that the sclera has less involvement in the pathogenesis of sCSC than in that of iCSC.
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影响因子：
4.1
作者：
Kuroda, Yoshimasa;Uji, Akihito;Yoshimura, Nagahisa
通讯作者：
Yoshimura, Nagahisa
DOI：
10.1097/iae.0b013e3181be0a83
发表时间：
2009-11-01
影响因子：
3.3
作者：
Imamura, Yutaka;Fujiwara, Takamitsu;Spaide, Richard F.
通讯作者：
Spaide, Richard F.
DOI：
10.1097/iae.0000000000001380
发表时间：
2017-08-01
影响因子：
3.3
作者：
Honda, Shigeru;Miki, Akiko;Nakamura, Makoto
通讯作者：
Nakamura, Makoto
DOI：
10.1097/00006982-199911000-00005
发表时间：
1999-01-01
影响因子：
3.3
作者：
Iida, T;Kishi, S;Shimizu, K
通讯作者：
Shimizu, K
DOI：
10.1007/s00417-004-0885-z
发表时间：
2004-09-01
影响因子：
2.7
作者：
Karadimas, P;Bouzas, EA
通讯作者：
Bouzas, EA