Chronic alcohol exposure and lactation: extended observations.
Chronic alcohol exposure and lactation: extended observations.
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慢性酒精暴露和哺乳期：长期观察。
DOI：
10.1016/s0741-8329(00)00081-1
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Subramanian,MG
中科院分区：
文献类型：
--
作者：
Heil,SH;Subramanian,MG
从我们的实验室以前的结果表明，慢性（8天）酒精给药抑制吸吮诱导的催乳素（PRL）释放30分钟的吸吮。此外，对母鼠长期给予酒精导致其窝仔生长迟缓。本研究旨在探讨长期哺乳（120分钟）对慢性酒精暴露后哺乳诱导的PRL释放的影响。此外，还检查了在酒精暴露期间观察到的生长迟缓是否在停止酒精输注后持续存在。在哺乳期第3天向母鼠植入心房导管，每天给予生理盐水或酒精（1.0或2.0 g/kg BW），持续8天（哺乳期第5天至第12天）。在给予初始酒精剂量后，以维持血液酒精水平（巴尔斯）所需的速率继续输注，每天持续4小时。测试在第12天进行。如前所述，哺乳30分钟后，在接受2.0 g/kg酒精的母鼠中，哺乳诱导的PRL释放受到抑制。然而，120分钟后的哺乳，PRL释放在这些大坝是远远高于控制或1.0克/公斤酒精大坝。此外，虽然在第8-16天，与其他两组母鼠窝仔相比，给予2.0 g/kg乙醇的母鼠窝仔的体重降低，但其体重反弹，并且在第18或20天与其他窝仔无差异。
Previous results from our laboratory have indicated that chronic (8 days) alcohol administration inhibits suckling-induced prolactin (PRL) release in response to 30 min of suckling. In addition, chronic alcohol administration to dams resulted in growth retardation of their litters. The present study was done to examine how an extended period of suckling (120 min) affected suckling-induced PRL release after chronic alcohol exposure. In addition, it was also examined whether the growth retardation observed during alcohol exposure persisted after alcohol infusions were discontinued. Dams were implanted with an atrial catheter on day 3 of lactation and saline or alcohol (1.0- or 2.0-g/kg BW) was administered daily for 8 days (lactation days 5 through 12). Following administration of the initial alcohol dose, the infusion was continued at rates required to maintain blood alcohol levels (BALs) for 4 h each day. Testing took place on day 12. As previously reported, suckling-induced PRL release was inhibited in dams receiving 2.0-g/kg alcohol after 30 min of suckling. However, after 120 min of suckling, PRL release in these dams was much higher than in either control or 1.0-g/kg alcohol dams. In addition, while the body weights of litters of dams administered 2.0-g/kg alcohol were reduced compared to litters of dams in the other two groups on days 8–16, their body weights rebounded and were not different from the other litters on days 18 or 20.
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酒精对哺乳大鼠哺乳诱导催乳素的急性抑制作用的模式和持续时间。
DOI：
10.1111/j.1530-0277.1990.tb01244.x
发表时间：
1990
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
Subramanian,MG;Chen,XG;Bergeski,BA
通讯作者：
Bergeski,BA
哺乳 2 至 90 分钟后大鼠垂体前叶和血浆催乳素 1 2
DOI：
10.3181/00379727-149-38892
发表时间：
1975
影响因子：
--
作者：
M. Subramanian;R. P. Reece
通讯作者：
R. P. Reece
酒精抑制哺乳大鼠哺乳诱导的催产素释放。
DOI：
10.1016/s0741-8329(99)00017-8
发表时间：
1999
期刊：
Alcohol (Fayetteville, N.Y.)
影响因子：
--
作者：
Subramanian,MG
通讯作者：
Subramanian,MG
慢性乙醇摄入诱导哺乳期大鼠乳腺上皮细胞超微结构的改变。
DOI：
10.1111/j.1530-0277.1989.tb00297.x
发表时间：
1989
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
S. Vilaró;O. Viñas;X. Remesar
通讯作者：
X. Remesar
乙醇消耗对大鼠哺乳期乳腺影响的形态测量研究。
DOI：
10.1111/j.1530-0277.1989.tb00313.x
发表时间：
1989
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
Steven,WM;Bulloch,B;SeeligJr,LL
通讯作者：
SeeligJr,LL