Oral Lichen Planus: An Update on Etiology, Pathogenesis, Clinical Presentation, Diagnosis and Management.
Oral Lichen Planus: An Update on Etiology, Pathogenesis, Clinical Presentation, Diagnosis and Management.
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DOI：
10.4103/0019-5154.156315
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发表时间：
2015-05
影响因子：
1.7
通讯作者：
Jawanda MK
中科院分区：
文献类型：
--
作者：
Gupta S;Jawanda MK
口腔是健康或疾病的一面镜子，是哨兵或早期预警系统。口腔很可能被认为是身体的窗口，因为口腔症状伴随着许多全身性疾病。在许多情况下，口腔受累先于其他部位出现其他症状或病变。口腔扁平苔藓（OLP）是一种慢性粘膜皮肤病的层状鳞状上皮疾病，病因不明，影响口腔和生殖器粘膜，皮肤，指甲和头皮。据估计，LP会影响总人口的0.5%至2.0%。本病最常见于30-60岁的中年患者，女性比男性更常见。该疾病似乎由抗原特异性机制介导，激活细胞毒性T细胞，以及非特异性机制，如肥大细胞脱颗粒和基质金属蛋白酶活化。正确认识该病的发病机制、临床表现和诊断对提供正确的治疗至关重要。本文讨论了口腔LP的患病率、病因、临床特点、口腔表现、诊断、并发症及治疗。
The mouth is a mirror of health or disease, a sentinel or early warning system. The oral cavity might well be thought as a window to the body because oral manifestations accompany many systemic diseases. In many instances, oral involvement precedes the appearance of other symptoms or lesions at other locations. Oral lichen planus (OLP) is a chronic mucocutaneous disorder of stratified squamous epithelium of uncertain etiology that affects oral and genital mucous membranes, skin, nails, and scalp. LP is estimated to affect 0.5% to 2.0% of the general population. This disease has most often been reported in middle-aged patients with 30-60 years of age and is more common in females than in males. The disease seems to be mediated by an antigen-specific mechanism, activating cytotoxic T cells, and non-specific mechanisms like mast cell degranulation and matrix metalloproteinase activation. A proper understanding of the pathogenesis, clinical presentation, diagnosis of the disease becomes important for providing the right treatment. This article discusses the prevalence, etiology, clinical features, oral manifestations, diagnosis, complications and treatment of oral LP.
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口服地衣披针形：发病机理和治疗的最新消息。
DOI：
10.4103/0973-029x.84474
发表时间：
2011-05
期刊：
Journal of oral and maxillofacial pathology : JOMFP
影响因子：
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作者：
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DOI：
10.1016/j.tripleo.2004.04.012
发表时间：
2004-12-01
期刊：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
影响因子：
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影响因子：
0.9
作者：
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影响因子：
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通讯作者：
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影响因子：
3.3
作者：
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通讯作者：
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