Improving Diagnostic Accuracy in Food Allergy.

Improving Diagnostic Accuracy in Food Allergy.
复制标题

DOI:
10.1016/j.jaip.2020.09.037
复制
发表时间:
2021-01
期刊:
The journal of allergy and clinical immunology. In practice
影响因子:
--
通讯作者:
Santos AF
Santos AF
中科院分区:
其他
文献类型:
--
作者:
Foong RX;Dantzer JA;Wood RA;Santos AF

文献摘要

参考文献

被引文献

相似文献

食物过敏的诊断会对患者和家人的生活产生重大影响,对患者的饮食和社交活动施加限制。另一方面,误诊可能会使患者面临潜在的严重过敏反应的风险。因此,准确诊断食物过敏至关重要。食物过敏的诊断通常结合临床病史和过敏原特异性 IgE 来确定;然而,如果没有明确的过敏反应史,IgE 致敏试验的解释可能会很困难。在没有 IgE 致敏的情况下,也有罕见的临床食物过敏病例。因此,理想情况下,疑似食物过敏测试需要进行口腔食物挑战(OFC),这是目前诊断食物过敏的黄金标准测试。由于 OFC 非常耗时,并且存在严重程度不可预测的急性过敏反应的风险,因此问题仍然存在:在将患者转诊至 OFC 之前,我们如何提高诊断的准确性?在此,我们回顾了用于支持食物过敏诊断的不同测试的预测价值,讨论了对治疗和预后的影响,并提出了一种应用于临床实践的诊断方法。
The diagnosis of food allergy can have a major impact on the lives of patients and families, imposing dietary restrictions and limitations on social activities. On the other hand, misdiagnosis can place the patient at risk of a potentially severe allergic reaction. Therefore, an accurate diagnosis of food allergy is of utmost importance. The diagnosis of food allergy is often established by the combination of the clinical history and allergen-specific IgE; however, without a clear history of an allergic reaction, the interpretation of IgE sensitization tests can be difficult. There are also rare cases of clinical food allergy in the absence of IgE sensitization. For that reason, testing for suspected food allergy ideally requires access to oral food challenges (OFCs), which are currently the gold standard tests to diagnose food allergy. As OFCs are time consuming and involve the risk of acute allergic reactions of unpredictable severity, the question remains: how can we improve the accuracy of diagnosis before referring the patient for an OFC? Herein, we review the predictive value of different tests used to support the diagnosis of food allergy, discuss implications for therapy and prognosis, and propose a diagnostic approach to be applied in clinical practice.
DOI: 10.2500/ar.2015.6.0135
发表时间: 2015-01
期刊: Allergy & rhinology (Providence, R.I.)
影响因子: --
作者:
Bartnikas LM;Sheehan WJ;Tuttle KL;Petty CR;Schneider LC;Phipatanakul W
通讯作者: Phipatanakul W
DOI: 10.1016/j.jaci.2010.10.007
发表时间: 2010-12
期刊: The Journal of allergy and clinical immunology
影响因子: --
作者:
NIAID-Sponsored Expert Panel;Boyce JA;Assa'ad A;Burks AW;Jones SM;Sampson HA;Wood RA;Plaut M;Cooper SF;Fenton MJ;Arshad SH;Bahna SL;Beck LA;Byrd-Bredbenner C;Camargo CA Jr;Eichenfield L;Furuta GT;Hanifin JM;Jones C;Kraft M;Levy BD;Lieberman P;Luccioli S;McCall KM;Schneider LC;Simon RA;Simons FE;Teach SJ;Yawn BP;Schwaninger JM
通讯作者: Schwaninger JM
DOI: 10.1111/cea.13291
发表时间: 2019-01
期刊: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
影响因子: --
作者:
Ehlers AM;Blankestijn MA;Knulst AC;Klinge M;Otten HG
通讯作者: Otten HG
DOI: 10.1111/all.12820
发表时间: 2016-04-01
期刊: ALLERGY
影响因子: 12.4
作者:
Eller, E.;Mortz, C. G.;Bindslev-Jensen, C.
通讯作者: Bindslev-Jensen, C.
DOI: 10.1016/j.jaci.2014.01.024
发表时间: 2014-07
影响因子: 14.2
作者:
Commins, Scott P.;James, Hayley R.;Stevens, Whitney;Pochan, Shawna L.;Land, Michael H.;King, Carol;Mozzicato, Susan;Platts-Mills, Thomas A. E.
通讯作者: Platts-Mills, Thomas A. E.